الموقع الشخصي لـ

صبحي محمد جمعه محمد

رئيس قسم الكيمياء - كلية العلوم

آخر الأبحاث العلمية

1.       Fathy M. Abdelrazek, Sobhi M. Gomha, M.E. B. Shaaban, Aziza I. lotfi, Heba N. El-Shemy. A facile synthesis of some novel triazolo[3,4-b]thiadiazines and triazolo[4,3-b]tetrazines. Synth. Commun. 2018, 34(1), 32-37.

2.        Abdou O. Abdelhamid, Sobhi M. Gomha, Nadia A. Abdelrehem, Ahmed M. Shalaby, Sahar M Kandeel. Synthesis and biological evaluation of some novel thiadiazole-benzofuran hybrids as potential antitumor agents. Synth. Commun. 2018, 48(6), 677–684.

3.        Salama A. Ouf, Sobhi M. Gomha, Mohamed M. Ewies, Ihab A. A. Sharawy. Synthesis, characterization and antifungal activity evaluation of some novel arylazothiazoles. J. Heterocycl. Chem., 2018, 55(1), 258-264.

4.        Sobhi M. Gomha, Zeinab A. Muhammad, M. R. Abdel-aziz, H. M. Abdel-aziz, H. M. Gaber, M. M. Elaasser. One pot synthesis of new thiadiazolyl-pyridines as anticancer and antioxidant agents. J. Heterocycl. Chem., 2018, 55, 530-536.

5.        Sobhi M. Gomha, Amany M. G. Mohamed, Y.H. Zaki, M.M. Ewies, Shaaban A. Elroby. Structural elucidation and antimicrobial evaluation of novel [1,2,4]triazolo[4,3-a]pyrimidines and pyrido[2,3-d][1,2,4]triazolo[4,3-a]pyrimidinones. J. Heterocycl. Chem. 2018, 55, 1147-1156.

6.       Sobhi M. Gomha, M. A. Abdallah, I. M. Abbas, M. S. H. Kazem. Synthesis, cytotoxicity evaluation, molecular docking and utility of novel chalcones as precursors for heterocycles incorporating pyrazole moiety. Med. Chem., 2018, 14(4), 344-355.

7.       Sobhi M. Gomha, Z.A. Muhammad, H. M. Abdel-aziz, E. E. El-Arab. Synthesis of new azoles and azolo-pyrimidines incorporating morpholine moiety as potent anti-tumor agents. Croat. Chem. Acta 2018, 91(1), 43–51.

8.       Sobhi M. Gomha, F. M. Abdelrazek, A. H. Abdelrahman, P. Metz. Synthesis of some new pyridine-based heterocyclic compounds with anticipated anti-tumor activity. J. Heterocycl. Chem. 2018, 55, 1729-1737.

9.       Sobhi M. Gomha, T. A. Farghaly, E. M. H. Abbas, Nadia T. Alqurashi. Terephthalaldehyde: An effecient key precursor for novel synthesis of some intresting bis-thiazoles and bis-triazolopyrimidinones. J. Heterocycl. Chem., 2018, 55, 750-755.

10.    Sobhi M. Gomha, Abdou O. Abdelhamid, Nadia A. Abdelrehem, Sahar M. Kandeel. Efficient Synthesis of new benzofuran-based thiazoles and investigation of their cytotoxic activity against human breast carcinoma cell lines. J. Heterocycl. Chem. 2018, 55, 995-1001.

11.     Sobhi M. Gomha, Zeinab A. Muhammad, Mohamad R. Abdel-aziz, Hassan M. Abdel-aziz. Hatem M. Gaber, Mahmoud M. Elaasser. One-pot synthesis of new thiadiazolyl-pyridines as anticancer and antioxidant agents. J. Heterocycl. Chem. 2018, 55, 530-536.

12.     H. R.M. Rashdan, Sobhi M. Gomha, M. S. El-Gendey, M. A. El-Hashash, Abdel Mohsen M. Soliman. Eco-friendly one-pot Synthesis of some new pyrazolo[1,2-b]phthalazinediones with antiproliferative efficacy on human hepatic cancer cell lines. Green Chem. Lett. and Reviews, 2018, 11(3), 264–274.

13.     Sobhi M. Gomha, M. S. El-Gendy, Z. A. Muhammad, A. O Abdelhamid, M. M. Abdel-Aziz. Utility of bis-hydrazonoyl chlorides as precursors for synthesis of new functionalized bis-thiadiazoles as potent antimicrobial agents. J. Heterocycl. Chem. 2018, 55, 844-851.

14.     Sobhi M. Gomha, M. M. Edrees, Z. A. Muhammad, Ahmed A. M. El-Reedy. 5-(Thiophen-2-yl)-1,3,4-thiadiazole derivatives: synthesis, molecular docking and in-vitro cytotoxicity evaluation as potential anticancer agents. Drug Design, Development and Therapy, 2018, 12, 1511-1523.

15.     Salama A. Ouf, Sobhi M. Gomha, M. M. Ewies, Ahmed S. Ouf, Ihab A. Sharawy. Efficiency of newly prepared thiazole derivatives against some cutaneous fungi. Bioorg. Med. Chem. 2018, 26, 3287–3295.

16.     Fadhil B. Essa, Akram Bazbouz, Suzan Alhilalb, Salama A. Ouf and Sobhi M. Gomha. Synthesis and biological evaluation of an indole core-based derivative with potent antimicrobial activity. Res. on Chem. Intermediates, 2018, 44(9), 5345-5356.

17.     Sobhi M. Gomha, A.O. Abdelhamid, O. M. Kandil, S. M Kandeel, N. A. Abdelrehem. Synthesis and molecular docking of some novel thiazoles and thiadiazoles incorporating pyranochromene moiety as potent anticancer agents. Mini-Reviews in Medicinal Chemistry, 2018, 18(19), 1670-1682.

18.     Sobhi M. Gomha, Hassan M. Abdel-aziz, Ahmed A. M. El-Reedy. Facile synthesis of pyrazolo[3,4-c]pyrazoles bearing coumarine ring as anticancer agents. J. Heterocycl. Chem. 2018, 55(8), 1960-1965.

19.     Sobhi M. Gomha, Zeinab A. Muhammad, Ahmed A. M. El-Reedy. Intramolecular ring transformation of bis-oxadiazoles to bis-thiadiazoles and investigation of their anticancer activities. J. Heterocycl. Chem. 2018, 55 (10), 2360-2367.

20.     Ziqi Tao, Sobhi M. Gomha, Mohamed G. Badrey, Tamer T. El-Idreesy, Taha M. A. Eldebss. Novel 4-heteroaryl-antipyrines: synthesis, molecular docking and evaluation as potential anti-breast cancer agents. J. Heterocycl. Chem. 2018, 55(10), 2408-2416.

21.     M. M. Edrees, S. Abu-Melha, A. M. Saad, N. A. Kheder, Sobhi M. Gomha, Z. A. Muhammad. Eco-Friendly synthesis, characterization and biological evaluation of some novel pyrazolinescontaining thiazole moiety as potential anticancer and antimicrobial agents. Molecules, 2018, 23, 2970.

22.     H. M. Gaber, Sobhi M. Gomha, T.A. Farghaly, Z. A. Muhammad, Mark C. Bagley. Chemistry of α-(arylhydrazono)-β-ketoaldehydes: preparation and chemical reactivities. Curr. Org. Chem. 2018, 22, 2599-2633.

23.     Fathy M. Abdelrazek, Sobhi M. Gomha, Mohamed E. B. Shaaban, Kamal A. Rabee, Heba N. El- Shemy, Abanoub M. Abdallah, Peter Metz. One-pot three-component synthesis and molecular docking of some novel 2-thiazolylpyridines as potent antimicrobial agents. Mini-Reviews in Medicinal Chemistry, 2019, 19(6), 527-538.

24.     Safaa S. Hassan, Sobhi M. Gomha. Novel functionalized thiosemicarbazone ligands and their pd(ii) complexes: synthesis, characterization, antibacterial and cytotoxic activities. Chemical Papers, 2019, 73 (2), 331-344.

25.     A. O. Abdelhamid, Sobhi M. Gomha, W. A. M. A. El-Enany. Convenient and efficient method for synthesis of bis-hetaryl ketones and evaluation of their antimicrobial activity. J. Heterocycl. Chem. 2019, 56(2), 426-433.

26.    Abdou O. Abdelhamid, Sobhi M. Gomha, Waleed A. M. A. El-Enany. Efficient synthesis and antimicrobial evaluation of new azolopyrimidines-bearing pyrazole moiety. J. Heterocycl. Chem. 2019, 56, 2487-2493.

27.     Khaled D. Khalil, Sayed M. Riyadh, Sobhi M. Gomha, Imran Ali. Synthesis, characterization and application of copper oxide chitosan nanocomposite for green regioselective synthesis of [1,2,3]triazoles. International Journal of Biological Macromolecules. 2019, 130, 928-937.

28.     Sobhi M. Gomha, M. M. Edress, Z. A. Muhammad, H.M. Gaber, M.M. Amin, Islam K. Matar. Synthesis under microwave irradiation and molecular docking of some novel bioactive thiadiazoles. Mini-Reviews in Medicinal Chemistry, 2019, 19(5), 437-447.

29.     Abdou O. Abdelhamid, Sobhi M. Gomha. The Chemistry of acetylpyrazoles and its utility in heterocyclic synthesis. J. Heterocycl. Chem. 2019, 56(3), 726-758.

30.     Sobhi M. Gomha, Hassan M. Abdel-aziz, Mohamed G. Badrey, Mohamed M. Abdulla. Efficient synthesis of some new 1,3,4-thiadiazoles and 1,2,4-triazoles linked to Pyrazolylcoumarin ring system as potent 5α-reductase inhibitors. J. Heterocycl. Chem. 2019, 56(4), 1275-1282.

31.     Abdelwahed R. Sayed, Sobhi M. Gomha, Fathy M. Abdelrazek, Mohamed S. Farghaly, Shaimaa A. Hassan, Peter Metz. Design, efficient synthesis and molecular docking of some novel thiazolyl-pyrazole derivatives as anticancer agents. BMC Chemistry, 2019, 13(1), 116.

32.     Huda K. Mahmoud, Refaie M. Kassab, Sobhi M. Gomha. Synthesis and characterization of some novel bis-thiazoles. J. Heterocycl. Chem. 2019, 56, 3157-3163.

33.     Sraa Abu-Melha, Mastoura M. Edrees, Heba H. Salem, Nabila A. Kheder, Sobhi M. Gomha, Mohamad R. Abdelaziz. Synthesis and biological evaluation of some novel thiazole-based heterocycles as potential anticancer and antimicrobial agents. Molecules 2019, 24, 539.

34.    Hassan M. Abdel-aziz, Sobhi M. Gomha, Abdelaziz A. El-Sayed, Abdulrhman Alsayari, Abdullatif  Bin Muhsinah, Yahia Nasser Mabkhot. Facile synthesis and antiproliferative activity of new 3-cyanopyridines. BMC Chemistry, 2019, 13(1), 137.

35.    Waleed A. M. A. El-Enany, Sobhi M. Gomha, Ahmed K El-Ziaty, Wesam Hussein, Mohamed M. Abdulla, Shaimaa A. Hassaan, Hanan A. Sallam and Rania S. Ali. Synthesis and molecular docking of some new bis-thiadiazoles as anti-hypertensive α-blocking agents. Synth.Commu. 2020, 50(1), 85-96.

36.    Sobhi M. Gomha, Zeinab A. Muhammad, Hassan M. Abdel-aziz, Islam K. Matar, Abdelaziz A. El-Sayed. Green synthesis, molecular docking and anticancer activity of novel 1,4-dihydropyridine-3,5-dicarbohydrazones under grind-stone chemistry. Green Chem. Lett. and Reviews, 2020, 13(1), 6–17.

37.    Abdelwahed R. Sayed, Sobhi M. Gomha, Eman A. Taher, Zeinab A. Muhammad, Hesham R. El-Seedi, Hatem M. Gaber, Mahgoub M. Ahmed. One-Pot Synthesis of Novel Thiazoles as Potential Anti- Cancer Agents. Drug Design, Development and Therapy, 2020, 14, 1363–1375.

38.    Abdelwahed R. Sayed, M. S. M. Ahmed, Sobhi M. Gomha. Efficient methods for the synthesis of novel arylazothiazoles based on acetylferrocene or adamantane. Curr. Org. Synth. 2020, 17, 282-287.

39.    Abdelwahed R. Sayed, Sukinah H. Ali, Sobhi M. Gomha, Yasair S. Al-Faiyz. Review of the synthesis and biological activity of hydrazonoyl halides. Review. Synth. Commu. 2020, 50(21), 3175–3203.

40.    Sobhi M. Gomha, H. M. Abdel-aziz, T. Z. Abolibda, Shaimaa A. Hassan, M.M. Abdalla. Green synthesis, molecular docking and pharmacological evaluation of new triazolo-thiadiazepinylcoumarine derivatives as sedative-hypnotic scaffold. J. Heterocycl. Chem.2020, 57, 1034–1043.

41.    Fathy M. Abdelrazek, Sobhi M. Gomha, Hassan M. Abdel-aziz, Mohamed S. Farghaly, Peter Metz, Ahmed Abdel-Shafy. Efficient Synthesis and In-Silico study of some novel pyrido[2,3-d][1,2,4]triazolo[4,3-a]pyrimidine derivatives. J. Heterocycl. Chem. 2020, 57, 1759–1769.

42.     S. M. Riyadh, Sobhi M. Gomha. Two decades for synthesis of mono- and bis-aminomercapto[1,2,4]triazoles. Review. RSC advances 2020, 10, 24994-25012.

43.    Sobhi M. Gomha, Zeinab A. Muhammad, Elham Ezz El-Arab, Amira M. Elmetwally, Abdelaziz A. El-Sayed, Islam K. Matar. Design, synthesis, molecular docking study and anti-hepatocellular carcinoma evaluation of new bis-triazolothiadiazines. Mini-Reviews in Medicinal Chemistry, 2020, 20(9), 788-800.

44.     S.Abu-Melha, M.M. Edrees, S.M. Riyadh, M.R. Abdelaziz, A.A. Elfiky, Sobhi M. Gomha. Clean grinding technique: a facile synthesis and in silico antiviral activity of hydrazones, pyrazoles, and pyrazines bearing thiazole moiety against SARS-CoV-2 main protease (Mpro).Molecules 2020, 25, 4565.

45.    H.R.M. Rashdan A.H. Abdelmonsef, I. A. Shehadi, Sobhi M. Gomha, A. Mohsen M. Soliman, H.K. Mahmoud. Synthesis, molecular docking screening and anti-proliferative potency evaluation of some new imidazo[2,1-b]thiazole linked thiadiazole conjugates. Molecules, 2020, 25, 4997.

46.     Salama A. Ouf, Sobhi M. Gomha, Mohamed M. Ewies, Ahmed S. Ouf, Ihab A. A. Sharawy. Antidermatophytic activity of some newly synthesized arylhydrazonothiazoles conjugated with monoclonal antibody. Scientific Reports 2020, 10, 20863.

47.    M. Shaban, Sobhi M. Gomha, Synthesis and Characterization of Nano Au/NPAA Templates. JESC. 2020, II (2), 147-155.

48.     Sobhi M. Gomha, H. A. Abdelhady, D. Z. H. Hassain, A. H. Abdelmonsef, M. El-Naggar, Mahmoud M. Elaasser, Huda K. Mahmoud. Thiazole based thiosemicarbazones: synthesis, cytotoxicity evaluation and molecular docking study. Drug Design, Development and Therapy, 2021, 15, 659–677.

49.    Mohammad Alhilal, Yaser A. M. Sulaiman, Suzan Alhilal, Sobhi M. Gomha, Salama A. Ouf. Antifungal activity of new diterpenoid alkaloids isolated by different chromatographic methods from Delphinium peregrinum L. var. eriocarpum Boiss. Molecules 2021, 26, 1375. 

50.    Sraa Abu-Melha, Zeinab A. Muhammad, Amr S. Abouzid, Mastoura M. Edrees, Ahmed S. Abo Dena, Sara Nabil, Sobhi M. Gomha. Multicomponent synthesis, DFT calculations and molecular docking studies of novel thiazolyl-pyridazinones as potential antimicrobial agents against antibiotic-resistant bacteria. J. Molecular Structure 2021, 1234,130180.

51.    L. A. Alshabanah, Sobhi M. Gomha, L. A. Al-Mutabagani, T. Z. Abolibda, N. A. Abd El-Ghany, W.A. M. A. El-Enany, A. K El-Ziaty, R. S. Ali, N. A. Mohamed. Cross-linked chitosan/multi-walled carbon nanotubes composite as ecofriendly biocatalyst for synthesis of some composite as ecofriendly biocatalyst for synthesis of some novel benzil bis-thiazoles. Polymers, 2021, 13, 1728.

52.    Laila A. Al-Mutabagani, Latifah A. Alshabanah, Sobhi M. Gomha, Hoda A. Ahmed. Synthesis, thermal and optical characterizations of new lateral organic systems. Crystals 2021, 11(5), 551.

53.    Abdelwahed R. Sayed, Hany M Abd El-lateef, Sobhi M. Gomha, Tariq Z.Abolibda. L-Proline catalyzed green synthesis and anticancer evaluation of novel bioactive benzil bis-hydrazones under grinding technique. Green Chem. Lett. and Reviews, 2021, 14 (2), 179–188.

54.    F. M. Abdelrazek, Sobhi M. Gomha, M. S. Farghaly, Peter Metz. One-pot, three-component synthesis of pyrido[2,3-d]pyrimidinones using aluminate sulfonic acid nanocatalyst under grinding technique. Polycyclic Aromatic Compounds 2021, 41(7), 1472-1482.

55.    Abeer S. Altowyan, Hoda A. Ahmed, Sobhi M. Gomha, Ayman M. Mostafa. Optical and thermal investigations of new Schiff base/ester systems in pure and mixed states. Polymers, 2021, 13, 1678.  

56.    Hany Abd El-Lateef, Abdelwahed R. Sayed, Sobhi M. Gomha, K. Shalabi. Synthesis and study of poly[(hydrazinylazo)]thiazoles as potent corrosion inhibitors for cast iron-carbon alloy in molar HCl: A collective computational and experiential methods. Journal of Molecular Liquids, 2021, 337, 116555.

57.    Huda K. Mahmoud, Sobhi M. Gomha, T. A. Farghaly, Hanem M. Awad. Synthesis of thiazole Linked thiazolo[2,1-b]thiazoles as antitumor agents. Polycyclic Aromatic Compounds 2021, 41(8), 1608–1622.

58.    Sobhi M. Gomha, Hoda A. Ahmed, Mohamed Shaban, Tariq Z. Abolibda, Muna S. Khushaim and Khalid A. Alharbi. Synthesis, Optical Characterizations and solar energy applications of new schiff base materials. Materials 2021, 14, 3718. 

59.    S. Abu-Melha, Sobhi M. Gomha, A. S. Abouzied, M. M. Edrees, A. S. Abo Dena, Z. A. Muhammad. Microwave-assisted one pot three-component synthesis of novel bioactive thiazolyl-pyridazinediones as potential antimicrobial agents against antibiotic-resistant bacteria. Molecules 2021, 26, 4260. 

60.    W. A. M. A. El-Enany, Sobhi M. Gomha,  W. Hussein, H.A. Sallam, R. S. Ali and Ahmed K El-Ziaty. Synthesis and biological evaluation of some novel bis-thiadiazoles as antimicrobial and antitumor agents. Polycyclic Aromatic Compounds 2021, 41, 2071–2082.

61.    Fowzia S. Alamro, Sobhi M. Gomha, Mohamed Shaban, Abeer S. Altowyan, Tariq Z. Abolibda, Hoda A. Ahmed. Optical investigations and photoactive solar energy applications of new synthesized Schiff base liquid crystal derivatives. Scientific Reports 2021, 11, 15046.

62.    Latifah A. Alshabanah, Laila A. Al-Mutabagani, Sobhi M. Gomha, Hoda A. Ahmed,  Saheed A. Popoola, Mohamed Shaban. Novel sulphonic acid liquid crystal derivatives; experimental, computational and optoelectric characterizations. RSC Advances, 2021, 11, 27937-27949.

63.    Huda K. Mahmoud, Ashraf A. Abbas, Sobhi M. Gomha. Synthesis, antimicrobial evaluation and molecular docking of new functionalized bis(1,3,4-thiadiazole) and bis(thiazole) derivatives. Polycyclic Aromatic Compounds 2021, 41(9), 2029–2041.

64.    R. M. Kassab, Sobhi M. Gomha, Z. A. Muhammad, A. S. El-khouly. Synthesis, biological profile, and molecular docking of some new bis-fused imidazole templates and investigation of their cytotoxic potential as anti-tubercular and/or anticancer prototypes. Medicinal Chemistry 2021, 17(8), 875-886.

65.    Sraa Abu-Melha, Mastoura M. Edrees, Sobhi M. Gomha, Sayed M. Riyadh, Waleed A. M. A. El-Enany, Aboubakr H. Abdelmonsef. Bioactive scaffolds: synthesis and in silico antibacterial activity of bis-azoles and N-bridged bis-fused azoles. Der Pharmacia Lettre 2021, 13, 67-78.

66.    Laila A. Al-Mutabagani, Fathy M. Abdelrazek, Sobhi M. Gomha, Ali S. Hebishy, Mohamed S. Abdelfattah, Safaa M. Hassan, Abdelwahed R. Sayed  and Mahmoud M. Elaasser. Synthesis and biological evaluation of thiazolyl-ethylidene hydrazino-thiazole derivatives: a novel heterocyclic system. Applied Sci. 2021, 11, 8908.

67.    Fowzia S. Alamro, Hoda A. Ahmed, Saheed A. Popoola,  Hamud A. Altaleb, Khulood A. Abu Al-Ola, Sobhi M. Gomha.  Effect of the relative positions of di-laterally substituted Schiff base derivatives: Phase transition and computational investigations. Crystals 2021, 11, 870.

68.    Sobhi M. Gomha, Hoda A. Ahmed, Mohamed Shaban, Tariq Z. Abolibda, Khalid Abdulaziz Alharbi, Hafsa H. Alalawy. New nematogenic conical‑shaped supramolecular H‑bonded complexes for solar energy investigations. Scientific Reports 2021, 11, 17622.

69.    Refaie M. Kassab, Sobhi M. Gomha, Sami A. Al-Hussain, Ahmed S. Abo Dena, Marwa M. Abdel-Aziz, Magdi E. A. Zaki, Zeinab A. Muhammad. Synthesis and in-silico studies of new bis-thiazole derivatives and their preliminary antimicrobial activity. Arabian J. Chem. 2021,  14, 103396.  

70.    Fowzia S. Alamro, Hoda A. Ahmed, Sobhi M. Gomha, M. Shaban. Synthesis, mesomorphic and solar energy characterizations of new non-symmetrical Schiff base Systems. Front. Chem. 2021, 9, 686788.

71.    Laila A. Al-Mutabagani, Latifah A. Alshabanah, Sobhi M. Gomha, Tariq Z. Abolibda, Mohamed Shaban, Hoda A. Ahmed. Synthesis, mesomorphic and electrical investigations of new furan liquid crystal derivatives. Front. Chem., 2021, 9, 711862.      

72.    Sobhi M. Gomha, M.M. Edrees, Z. A. Muhammad, Nabila A. Kheder, S. Abu-Melha, A. M. Saad. Synthesis, characterization and antimicrobial evaluation of some new 1,4-dihydropyridines-1,2,4-triazole hybrid compounds. Polycyclic Aromatic Compounds 2022, 42(1), 173-185.

73.    Sobhi M. Gomha, Zeinab A. Muhammad, Sami A. Al-Hussain, Magdi E. A. Zaki, Hassan M. Abdel-aziz. Synthesis, Characterization and antimicrobial evaluation of some new 1,4-dihydropyridine hybrid with 1,3,4-thiadiazole. Polycyclic Aromatic Compounds 2022, 42(4), 1697-1709.

74.    Hany M. Abd El-Lateef, K. Shalabic, A. R. Sayed, Sobhi M. Gomha, Esam M. Bakir. The novel polythiadiazole polymer and its composite with α-Al(OH)3 as inhibitors for steel alloy corrosion in molar H2SO4: experimental and computational evaluations. Journal of Industrial and Engineering Chemistry 2022, 105, 238-250.

75.    Sraa Abu-Melha, Mastoura M. Edrees, Musa A. Said, Sayed M. Riyadh, Nadia S. Al-Kaff, Sobhi M. Gomha. Potential COVID-19 drug candidates based on dia-zinyl-thiazol-imine moieties: synthesis and greener pastures biological study. Molecules 2022, 27, 488.

76.    S.Abu-Melha, M. M. Edrees, N. A. Kheder, A. M. Saad, S. M. Riyadh, M. M. Abdel-Aziz, M. A. Abdelmoaz, and Sobhi M. Gomha. Synthesis and anti-tubercular (tb) evaluation of bis-[4-ethylidineamino[1,2,4]triazole-3-thiol]tethered by 1,4-dihydropyridine. Russian J. Bioorg. Chem., 2022, 48(2), 345–352.

77.    Mohamed A. Abdelgawad, Nadia A.A. Elkanzi, A. A. Nayl, Arafa Musa, Nasser Hadal Alotaibi, W. A. A. Arafa, Sobhi M. Gomha and Rania B. Bakr. Targeting tumor cells with pyrazolo[3,4-d]pyrimidine scaffold: A literature review on synthetic approaches, structure activity relationship, structural and target-based mechanisms. Review. Arabian J. Chem, 2022, 15, 103781.

78.    F. S. Alamro, N. S. Al-Kadhi, S. M. Gomha, S. A. Popoola, M. S. Khushaim, O. A. Alhaddad, H. A. Ahmed. Experimental and theoretical investigations of three ring ester/azomethine materials. Materials, 2022, 15, 2312.

79.    A. A. Nayl, A. I. Abd-Elhamid, Nasser. S. Awwad, Mohamed A. Abdelgawad, Jinglei Wu, Xiumei Mo, Sobhi M. Gomha, Ashraf A.Aly, Stefan Bräse. Recent progress and potential biomedical applications of electrospun nanofibers in regeneration of tissues and organs. Review. Polymer, 2022, 14, 1508.

80.    A. A. Nayl, A. I. Abd-Elhamid, Nasser. S. Awwad, Mohamed A. Abdelgawad, Jinglei Wu, Xiumei Mo, Sobhi M. Gomha, Ashraf A. Aly, Stefan Bräse. Review of the Recent Advances in Electrospun Nanofibers Applications in Water Purification. Review. Polymer 2022, 14, 1594.

81.    L. A. Alshabanah, L. A. Al-Mutabagani, Sobhi M. Gomha, H. A. Ahmed. Three-component synthesis of some new coumarin derivatives as anti-cancer agents. Front. Chem. 2022, 9, 762248.

82.    A. A. Nayl, Wael A. A. Arafa. M. Ahmed, A. I. Abd-Elhamid, E. M. El-Fakharany, M.A. Abdelgawad,  Sobhi M. Gomha, Hamada M. Ibrahim, Ashraf A. Aly, Stefan Bräse, Asmaa K. Mourad. Novel pyridinium based ionic liquid promoter for aqueous knoevenagel condensation: green and efficient synthesis of new derivatives with their anticancer evaluation. Molecules 2022, 27, 2940.

83.    Omaima A. Alhaddad, Muna S. Khushaim, Magdi M. Naoum, Sobhi M. Gomha, Hoda A. Ahmed. Mesophase behavior of four ring ester/azomethine/ester liquid crystals in pure and mixed states. Liquid Crystal, 2022, 49 (10), 1395–1402.

84.    M. Alhilal, Suzan Alhilal, Sobhi M. Gomha, Salama A. Ouf. Isocarpine as a new peperidine alkaloid from adenocarpus complicatus with anticandidal activity. Nat. Product J. 2022, 12(5), 79-92.

85.    S.M. Riyadh, T. Z. Abolibda, A. R. Sayed, Sobhi M. Gomha. Synthetic utility of aminomercapto [1,2,4]triazoles in the preparation of fused triazoles. Review. Curr. Org. Chem. 2022, 26(7), 693-714.         

86.    H. K. Mahmoud, A. R. Sayed, M. M. Abdel-Aziz, Sobhi M. Gomha. Synthesis of new thiazole clubbed imidazo[2,1-b]thiazole hybrid as antimycobacterial agents. Med. Chem., 2022, 18, 1100-1108.

87.    A.R. Sayed, Hany Elsawy, Saad Shaaban, Sobhi M. Gomha, Yasair S. Al-Faiyz.  Design, synthesis, and biological evaluations of novel azothiazoles based on thioamide. Curr. Issues Mol. Biol. 2022, 44, 2956–2966.

88.    Jehan Y. Al-Humaidi, Mohamed G. Badrey, Ashraf A. Aly, AbdElAziz A. Nayl, Mohie E. M. Zayed, Ohoud A. Jefri, Sobhi M. Gomha. Evaluation of the binding relationship of the RdRp enzyme to novel thiazole/ acid hydrazone hybrids obtainable through green synthetic procedure. Polymer, 2022, 14, 1594.

89.    Sobhi M. Gomha, Sayed M. Riyadh, Bader Huwaimel, Mohie E. M. Zayed, Magda H. Abdellattif. Synthesis, molecular docking study and cytotoxic activity on mcf cells of some new thiazole clubbed thiophene scaffolds. Molecules, 2022, 27, 4639.

90.    N.S. Al-Kadhi, F. S. Alamro, S. A. Popoola, Sobhi M. Gomha, Noha S. Bedowr, Hoda A. Ahmed. Novel imidazol liquid crystals; experimental and computational approaches. Molecules, 2022, 27, 4607.

91.    Musa A. Said, Sayed M. Riyadh, Nadia S. Al-Kaff, A. A. Nayl, Kh. D. Khalil, Stefan Bräse, Sobhi M. Gomha. Synthesis and Greener Pastures Biological Study of Bis-thiadiazoles as Potential Covid-19 Drug Candidates. Arabian J. Chem. 2022, 15(9), 104101.

92.    Abdelwahed R. Sayed, Sobhi M. Gomha, Yasair S. Al-Faiyz, Yasser H. Zaki. New convenient routes of hydrazonoyl halides for the synthesis of novel thiazoles and polythiazoles. Polycyclic Aromatic Compounds 2022, 42(6), 3318–3332. 

93.    S. Alhilal, M. Alhilal, Sobhi M. Gomha, S. A. Ouf. Synthesis and biological evaluation of new aza-acyclic nucleosides and their hydrogen complexes from indole. Res. Chem. Intermed. 2022, 48, 3567–3587.

94.    Khaled D. Khalil, Hoda A Ahmed, Ali H. Bashal, Stefan Bräse, AbdElAziz Nayl, Sobhi M.Gomha. Efficient, recyclable, heterogeneous base nanocatalyst for thiazoles with chitosan capped calcium oxide nanocomposite. Polymer, 2022, 14, 3347.

95.    Mohammad Alhilal, Yaser A.M Sulaiman, Suzan Alhilal, Sobhi M. Gomha, Salama A. Ouf.  Synthesis of novel acyclic nucleoside analogue starting from 6-aminouracil as potent antimicrobial agent. Polycyclic Aromatic Compounds 2022, 42, 6463–6474.

96.    H. K. Mahmoud, Sobhi M. Gomha, H. A. Abdelhady, M. M. Elaasser, D. Z. H. Hassain. Microwave-assisted one-pot three component synthesis of some thiazolyl(hydrazonoethyl)thiazoles as potential anti-breast cancer agents. Polycyclic Aromatic Compounds 2022, 42(10), 7232–7246

97.    Amr S. Abouzied, Jehan Y. Al-Humaidi, Abdulrahman S. Bazaid, Husam Qanash, Naif K. Binsaleh,    Abdulwahab Alamri, Sheikh Muhammad Ibrahim, Sobhi M. Gomha. Synthesis, molecular docking study, and cytotoxicity evaluation of some novel 1,3,4-thiadiazole as well as 1,3-thiazole derivatives bearing a pyridine moiety. Molecules. 2022, 27, 6368.

98.    Ghadah F. Aljohania Tariq Z. Abolibda, Mohammad Alhilal, Jehan Y. Al-Humaidi, Suzan Alhilal, Hoda A. Ahmed, Sobhi M. Gomha. Novel thiadiazole-thiazole hybrids: synthesis, molecular docking, and cytotoxicity evaluation against liver cancer cell lines. Journal of Taibah University for Science 2022, 16(1), 1005–1015.

99.    Sobhi M. Gomha, Sayed M. Riyadh, Magda H. Abdellattif, Tariq Z. Abolibda, Hassan M. Abdel-aziz, A. A. Nayl, Alaa M. Elgohary, Abdo A. Elfiky. Synthesis and in silico study of some new bis-[1,3,4]thiadiazolimines and bis-thiazolimines as potential in-hibitors for SARS-CoV-2 main protease. Curr. Issues Mol. Biol. 2022, 44(10), 4540-4556.

100. Thoraya A. Farghaly, Amani M. R. Alsaedi, Jihan Qurban, A. A. Nayl, Sobhi M. Gomha. Hydrazonoyl halides as precursors for synthesis of bioactive heterocyclic compounds via reaction with aryl- and hetaryl-amines. Curr. Org. Chem. 2022, 27(15), 1431-1452.

101. Ferid Yaccoubi, Mohamed El-Naggar, Fathy M. Abdelrazek, Sobhi M. Gomha, Mohamed S. Farghaly, Tariq Z. Abolibda, Lobna A. Ali, Aboubakr H. Abdelmonsef. Pyrido-pyrimido-thiadiazinones: green synthesis, molecular docking studies and biological investigation as obesity inhibitors. Journal of Taibah University for Science 2022, 16(1), 1275-1286.

102. Tariq Z. Abolibda, Maher Fathalla, Basant Farag, Magdi E. A. Zaki, Sobhi M. Gomha. Synthesis and molecular docking of some novel 3-thiazolyl-coumarins as inhibitors of VEGFR-2 kinase. Molecules, 2023, 28(2), 689.

103. Adel Alghamdi, Amr S. Abouzied, Abdulwahab Alamri, Sirajudheen Anwar, Mukhtar Ansari, Ibrahim Khadra,Yasser H. Zaki, Sobhi M. Gomha. Synthesis, molecular docking, and dynamic simulation targeting main protease (mpro) of new, thiazole clubbed pyridine scaffolds as potential COVID-19 inhibitors. Curr. Issues Mol. Biol. 2023, 45(2), 1422-1442.

104. Sobhi M. Gomha, Sayed M. Riyadh, Reem A. K. Alharbi, Magdi E. A. Zaki, Tariq Z. Abolibda, Basant Farag. Green route synthesis and molecular docking of azines using cellulose sulfuric acid under microwave irradiation. Crystals 2023, 13(2), 260.

105. Mohamed S. Ibrahim, Basant Farag, Jehan Y. Al-Humaidi, Magdi E. A. Zaki, Maher Fathalla, Sobhi M. Gomha. Mechanochemical synthesis and molecular docking studies of new azines bearing indole as anticancer agents. Molecules 2023, 28, 3869.

106. Sobhi M. Gomha, Sayed M. Riyadh, Thoraya A. Farghaly, Reda A. Haggam. Synthetic utility of bis-aminomercapto[1,2,4]triazoles in the preparation of bis-fused triazoles and macrocycles. Review. Polycyclic Aromatic Compounds 2023, 43(4), 3720–3740.

107. Jehan Y. Al-Humaidi, A. A. Nayl, Mohamed M. Abdalla, Sobhi M. Gomha. New convenient routes of synthesis and biological activity evaluation of some new coumarin derivatives as potent anticonvulsant and CNS depressant agents. Polycycl. Arom. Comp., 2023, 43(3), 2680–2689

108. Fayza O. Ashmawy, Sobhi M. Gomha, Magda A. Abdallah, Magdi E. A. Zaki, Sami A. Al-Hussain, Mohamed A. El-desouky. Synthesis, in vitro evaluation and molecular docking studies of novel thiophenyl thiazolyl-pyridine hybrids as potential anticancer agents. Molecules 2023, 28, 4270.

109. J. Y. Al-Humaidi, Sobhi M. Gomha, N. A. Abd El-Ghany, B. Farag, Magdi E. A. Zaki, T. Z. Abolibda, N. A. Mohamed. Green synthesis and molecular docking study of some new thiazoles using terephthalohydrazide chitosan hydrogel as ecofriendly biopolymeric catalyst. Catalysts, 2023, 13, 1311.

110. Abanoub Mosaad Abdallah, Sobhi M. Gomha, Magdi E. A. Zaki, Tariq Z. Abolibda, and Nabila A. Kheder.  A Green Synthesis, DFT calculations, and molecular docking study of some new indeno[2,1-b]quinoxalines containing thiazole moiety. Journal Molecular Structure 2023, 1292, 136044.

111. Tariq Z. Abolibda, Maher Fathalla, Ghadah F. Aljohani, Ehab M. Zayed, Sobhi M. Gomha. Synthesis and in silico antiviral activity of novel bioactive thiobarbituric acid-based hydrazones and pyrazoles against SARS-CoV-2 main protease (Mpro). Polycylic Aromatic Compounds 2023, 8, 7635-7650.

112. Khaled D. Khalil, Sayed M. Riyadh, Ali H. Bashal, Tariq Abolibda, Sobhi M. Gomha. Green synthetic approaches of 2-hydrazonothiazol-4(5H)-ones using sustainable barium oxide-chitosan Nanocomposite Catalyst. Polymer 2023, 15(18), 3817.

113. Jehan Y. Al-Humaidi, Sobhi M. Gomha, S.M. Riyadh, Mohamed S. Ibrahim, Magdi E. A. Zaki, T. Z. Abolibda, Ohoud A. Jefri, A.S. Abouzied. Synthesis, Biological Evaluation, and Molecular Docking of Novel Azolylhydrazonothiazoles as Potential Anticancer Agents. ACS Omega 2023 8(37), 34044-34058.

114. Sobhi M. Gomha, Magdi E. A. Zaki, Deepika Maliwal, Raghuvir R. S. Pissurlenkar, Mohamed S. Ibrahim, Maher Fathalla, Ahmed M. Hussein. Synthesis, In-Silico Studies, and Biological Evaluation of Some Novel 3-Thiazolyl-Indoles as CDK2–inhibitors. Results in Chemistry 2023, 6, 101209.

115. T. A. Farghaly, G. H. Alfaifi, Sobhi M. Gomha. Recent literature on the synthesis of thiazole derivatives and their biological activities. Review. Mini Rev Med. Chem. 2023, 24 (2), 196-251.

116. Hoda A. Ahmed, Tariq Z. Abolibda, Yasser A. M. Ismail, Abdullah Almohammedi, K. A. Aly, Mohamed S. Ibrahim, Sobhi M. Gomha. Novel maleic anhydride derivatives: liquid crystalline materials with enhanced mesomorphic and optical characteristics. Forntiers in Chemistry, 2023, 11, 1287883.

117. Mohamed G. Badrey, Sobhi M. Gomha, Aboubakr H. Abdelmonsef, Ahmed A. M. El-Reedy. Syntheses and molecular docking analysis of some new thiazole and thiazine derivatives as three armed molecules with a triazine ring as a core component: a search for antiobesity agents. Polycyclic Aromatic Compounds 2023, https://doi.org/10.1080/10406638.2023.2173617.

118. Sobhi M. Gomha, Fathy M. Abdelrazek, Jehan Y. Al-Humaidi, Amany M. Reyad, Hassan M. Abdel-aziz, Aboubakr H. Abdelmonseff. Synthesis, molecular docking study of some new thiazole-coumarin molecular hybrids as antibacterial agents. Current Organic Synthesis 2023, in press.

119. Jehan Y. Al-Humaidi, Sayed M. Riyadh, Basant Farag, Magdi E. A. Zaki, Tariq Z. Abolibda, Sobhi M. Gomha. Synthesis of Bis-thiazoles Tethered 1,4-Dihydropyridine and Pyridine linkers via Simple Oxidation and their Molecular Docking as VEGFR -TK Inhibitors. Curr. Med. Chem., 2023, in press.

120. Jehan Y. Al-Humaidi, Sobhi M. Gomha, AbdElAziz A. Nayl, Ashraf A. Aly, Mahmoud A. A. Ibrahime, Magdi E. A. Zakig, Stefan Bräseh, Reda A. Haggam. Synthesis, Characterization, and Molecular Modeling Studies of Novel Indenopyridazine-Thiazole Molecular Hybrids. Current Organic Synthesis, 2023, in press.

121. Refaie M. Kassab, Sami A. Al-Hussain, Aboubakr H. Abdelmonsef, Magdi E. A. Zaki, Sobhi M. Gomha, Zeinab A. Muhammad. Novel bis-thiazole derivatives as HSV-1 inhibitors through targeting surface glycoprotein d: an efficient synthesis, characterization, biological evaluation and molecular docking study. Future Medicinal Chemistry, 2023, in press 

122. Mahmoud A. Mohamed, Amr S. Abouzied, Amany M. Reyad, Magdi E. A. Zaki, Fathy Elsayed Abdelgawad, Sobhi M. Gomha. Novel Terpyridines as S. Aureus Gyrase Inhibitors: Efficient Synthesis & Antibacterial Assessment via Solvent-Drop Grinding. Future Medicinal Chemistry 2023, in press

123. Manar Ayman, Sobhi M. Gomha, Magda A. Abdallah,  Doaa E. ElNashar,  AbdelMohsen M. Soliman,  Huda R. M. Rashdan. In Sight into innovative cancer therapeutic approach based on nanotechnology: Chitosan (CS)/Polyvinyl alcohol (PVA) films loaded with synthesized bisthiazole derivative for cancer treatment.  Egyptian Journal of Chemistry 2023, in press

 

 

PUBLISHED BOOKS

https://www.amazon.com/s?i=stripbooks&rh=p_27%3ASobhi+Gomha&s=relevancerank&text=Sobhi+Gomha&ref=dp_byline_sr_book_1

1.      Sobhi M. Gomha, Sayed M. Riyadh. Synthesis of some new bioactive heterocycles. LAP Lambert Academic Publishing, 2020, ISBN: 978-620-0-78484-1.

2.      Sobhi M. Gomha, Sayed M. Riyadh, Elmahdi A. M. Abubaker. Synthesis and Biological Evaluation of Some New Pyrroles. LAP Lambert Academic Publishing, 2020, ISBN: 978-620-0-78618-0.

3.      Sobhi M. Gomha, Amany Mohamed, Kareem Mohamed. Synthesis and Antimicrobial Evaluation of New Fused Azines. LAP Lambert Academic Publishing, 2020, ISBN: 978-620-2-51329-6.

4.      Sobhi M. Gomha, Abdou Abdelhamid, Sahar Kandeel. Synthesis of Some Novel Bioactive Indoles as Anticancer Agents. LAP Lambert Academic Publishing, 2020, ISBN: 978-620-2-51660-0.

5.      Sobhi M. Gomha, Fathi M. Abdelrazek and, Heba N. El-Shemy. Synthesis of Some Novel Bioactive Fused 1,2,4-Triazole. LAP Lambert Academic Publishing, 2020, ISBN: 978-620-2-52077-5.

6.    Sobhi M. Gomha, Aziza I. lotfi, Heba N. El-Shemy. Extraction of Uranium and Thorium Ions from Acidic Solutions. LAP Lambert Academic Publishing, 2020, ISBN:  978-620-2-52075-1.

7.    Abdou Abdelhamid, Sobhi M. Gomha, S. Kandeel. Synthetic Approaches for Bioactive Compounds from Khellin and Visnagin. LAP Lambert Academic Publishing, 2020, ISBN: 978-620-2-51661-7.

8.      Sobhi M. Gomha, Mohammed A. Bauomi. Synthesis and Biological Evaluation of Some New Imidazoles.LAP Lambert Academic Publishing, 2020, ISBN: 978-620-2-51432-3.

9.    Sobhi M. Gomha,Abdou O. Abdelhamid, Waleed El-Enany. New Synthetic Strategy for Synthesis of Novel pyrazoles. LAP Lambert Academic Publishing, 2020, ISBN:978-620-2-52077-5.

10.  Sobhi M. Gomha, Magda A. Abdallah, Mahmoud Metwally. Pyridopyrimidines: Synthesis and Biological Activity. LAP Lambert Academic Publishing, 2020, ISBN: 978-620-2-52529-9.

11.  Sobhi M. Gomha, Magda A. Abdallah, Ikhlass M. Abbas. Pyrazoles: Synthesis and Biological Activity. LAP Lambert Academic Publishing, 2020, ISBN: 978-620-2-52530-5.

-   I awarded the prize of the best paper in heterocyclic chemistry from the Egyptian Heterocyclic Chemistry Society (E.H.C.S) for 2015.

-   I was included in the list of the World's Top 2% Scientists by Stanford University in 2019. https://elsevier.digitalcommonsdata.com/datasets/btchxktzyw/1

-   I was included in the list of the World's Top 2% Scientists by Stanford University in 2020 (I awarded the 1st rank in Organic Chemistry in Cairo University). https://elsevier.digitalcommonsdata.com/datasets/btchxktzyw/2

-   I was included in the list of the World's Top 2% Scientists by Stanford University in 2021(I awarded the 1st rank in Organic Chemistry in Cairo University). https://elsevier.digitalcommonsdata.com/datasets/btchxktzyw/3

-   In 2021: I awarded the 2nd  rank in Organic Chemistry (Cairo University) and 4th rank (Egypt) according to World Scientists and University Ranking 2021 (AD Scientific Index). https://www.adscientificindex.com/scientist.php?id=90816

-   I awarded certificates of appreciation from Cairo University for distinguished scientific publication for the years 2008-2020.

-   I awarded certificates of appreciation from Cairo University for distinguished scientific publishing (more than 10 research papers) for the years 2015: Top 10 publishers in Cairo University, Egypt.

-   I awarded certificates of appreciation from Cairo University for distinguished scientific publishing (more than 10 research papers) for the years 2016: Top 10 publishers in Cairo University, Egypt.

-   I awarded certificates of appreciation from Cairo University for distinguished scientific publishing (more than 10 research papers) for the years 2017: Top 10 publishers in Cairo University, Egypt.

-   I awarded certificates of appreciation from Cairo University for distinguished scientific publishing (more than 10 research papers) for the years 2018: Top 10 publishers in Cairo University, Egypt.

-   I awarded certificates of appreciation from Cairo University for distinguished scientific publishing (more than 10 research papers) for the years 2019: Top 10 publishers in Cairo University, Egypt.

-   I awarded certificates of appreciation from Cairo University for distinguished scientific publishing (more than 10 research papers) for the years 2020: Top 10 publishers in Cairo University, Egypt.


1.   Eco-friendly synthesis, characterization and biological evaluation of some novel pyrazolines containing thiazole moiety as potential anticancer and antimicrobial agents (2017-2018) and funding agency: the Deanship of Scientific Research (GRP‑68‑39) King Khalid University, KSA.

2.   The separation of rare earth elements from the beach monazite metal from the black sand for the field season 2017-2018 and approved by Resolution No. 497 of 2017. Funding agency: Nuclear Materials Authority, Kattameya, Egypt.

3.   Green synthesis and biological evaluation of some novel thiazole-based heterocycles as potential anticancer agents (2019-2020) and funding agency:  the Deanship of Scientific Research (Project Number 1811008) King Faisal University, KSA.

4.   Green synthesis of some novel thiazole-based heterocycles as anti-cancer agents (2019-2020) and funding agency:  the Deanship of Scientific Research (Project Number Takamel 11-86) Islamic University of Madinah, KSA.

5.   Synthesis of Innovative Optical Organic Compounds (2020-2021) and funding agency:  the Deanship of Scientific Research (the Program of research project funding after publication, Project Number PRFA-P-42-8) Princess Nourah bint Abdulrahman University, KSA.

6.   Green synthesis of some novel heterocyclic compounds as anti-cancer agents (2020-2021) and funding agency:  the Deanship of Scientific Research (the program of research project funding after publication, Project Number PRFA-P-42-9) Princess Nourah bint Abdulrahman University, KSA.

7.   Green synthesis of some novel thiazole-based heterocycles as anti-cancer agents (2019-2020) and funding agency:  the Deanship of Scientific Research (Project Number Takamel 11-86) Islamic University, KSA.

8.   Synthesis of Photo-active Innovative organic compounds to improve the photovoltaic and electrical properties of solar cells (2020-2021) and funding agency:  the Deanship of Scientific Research (Project Number Tammay 2-654) Islamic University of Madinah, KSA.