Latest scientific research
List of publications (2000 –March 2021)
1.
Ahmad S. Shawali, Sobhi M. Gomha. A new entry for short and
regioselective synthesis of [1,2,4]triazolo[4,3- b][1,2,4]-triazin-7(1H)-one. Advanced Synthesis and
Catalysis, 2000, 342, 599–604.
2.
Ahmad S. Shawali, Sobhi M. Gomha. Regioselectivity
in 1,5-electrocyclization of N-[as-triazin-3-yl]nitrilimines.
Synthesis of s-triazolo[4,3-b]-as-triazin-7(8H)-ones.
Tetrahedron, 2002, 58, 8559–8564.
3.
Magda A. Abdallah, Sayed M.
Riyadh, Ikhlass M. Abbas, Sobhi M. Gomha.
Synthesis and biological activities of 7-arylazo-7H-pyrazolo[5,1-c][1,2,4]triazolo-6(5H)-ones
and 7-arylhydrazono-7H-[1,2,4] triazolo[3,4-b][1,3,4]thiadiazines.
J. Chin. Chem. Soc., 2005, 52, 987-994.
4.
Ikhlass M. Abbas, Sayed M.
Riyadh, M. A. Abdallah, Sobhi M. Gomha.
A novel route to tetracyclic fused tetrazines and thiadiazines. J.
Heterocycl. Chem., 2006, 43, 935-942.
5.
Sayed M. Riyadh, Magda A.
Abdallah, Ikhlass M. Abbas, Sobhi M. Gomha.
A facile one–pot
synthesis of pyrido[3`,2`:4,5]thieno[3,2-d][1,2,4]triazolo[5,4-a]pyrimidin-5-one.
Inter. J. Pure & Applied Chem., 2006, 1, 57-64.
6.
Magda A. Abdallah, Sayed M.
Riyadh, Ikhlas M. Abbas, Sobhi M. Gomha.
Synthesis and antimicrobial activity of 3,
5-disubstituted-1,3,4-thiadiazol-2-yliden by the intramolecular ring
transformation of 1,3,4-oxadiazole. Inter. J. Pure & Applied Chem.,
2006, 1, 265-271.
7.
Sobhi
M. Gomha. A facile one-pot synthesis of
6,7,8,9-tetrahydrobenzo[4,5]thieno[2,3-d]-1,2,4-triazolo[4,5-a]pyrimidin-5-ones.
Monatsh. Chem., 2009, 140, 213-220.
8.
Sobhi
M. Gomha, Sayed M. Riyadh. Synthesis of triazolo[4,3-b][1,2,4,5]tetrazines
and triazolo[3,4-b][1,3,4]thiadiazines using chitosan as ecofriendly
catalyst under microwave irradiation. Arkivoc, 2009, (xi),
58-68.
9.
Hatem A. Abdel-Aziz, Sobhi M. Gomha. A new aspect of the Pfitzinger
reaction: Microwave-assisted synthesis of the new heterocyclic ring system
6-arylbenzo[4,5]imidazolo[2,1-b]quino[4,3-e]-1,3-thiazin-14-one. Z.
Naturforsch., 2009, 64b, 826- 830.
10.
Sayed M. Riyadh, Thoraya A.
Farghaly, Sobhi M. Gomha. Novel
polyazaheterocyclic systems: synthesis, antitumor, and antimicrobial
activities. Arch. Pharm. Res., 2010, 33(11),
1721-1728.
11.
Thoraya A. Farghaly, Sobhi M. Gomha.
Ethyl (1,3-diphenyl-1H-pyrazolo[4,3-e][1,2,4]triazolo-[1,5-c]pyrimidin-5-yl)acetate.
Molbank, 2011, M743.
12.
Sobhi
M. Gomha, Huwaida M.E. Hassaneen. Synthesis and antimicrobial
activity of some new pyrazoles, fused pyrazolo[3,4-d]-pyrimidine and 1,
2-dihydroimidazo-[2,1-c][1,2,4]triazin-6-one derivatives. Molecules, 2011, 16,
6549-6560.
13.
Sobhi M. Gomha, Thoraya A.
Farghaly. Synthesis of (E)-ethyl 3-(dimethylamino)-2-(7,9-diphenyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-acrylate.
Molbank, 2011, M746.
14.
Sobhi
M. Gomha, Sayed M. Riyadh. Synthesis under microwave irradiation
of [1,2,4]triazolo-[3,4-b][1,3,4]thiadiazoles and other diazoles bearing
indole moieties and their antimicrobial evaluation. Molecules, 2011,
16, 8244-8256.
15.
Thoraya A. Farghaly, Sobhi M. Gomha, Eman M. H. Abbas, Mohamed M.
Abdalla. Hydrazonoyl halides as precursors for new fused heterocycles of 5
α-reductase inhibitors. Archive Der Pharmazie, 2012, 345,
117–122.
16.
Mohamed G. Badrey, Sobhi M. Gomha.
3-Amino-8-hydroxy-4-imino-6-methyl-5-phenyl-4,5-dihydro-3H-chromeno[2,3-d]pyrimidine:
an efficient key precursor for novel synthesis of some interesting triazines
and triazepines as potential anti-tumor agents. Molecules, 2012, 17, 11538-11553.
17.
Sobhi M. Gomha, Thoraya A. Farghaly. Synthesis and X-ray crystal structure
of ethyl 3-(2-(3-methyl-1H-indole-2-carbonyl)hydrazono)butanoate. Molbank,
2012, M749.
18.
Sobhi
M. Gomha, Hatem A. Abdel-Aziz. Synthesis of new
heterocycles derived from 3-(3-methyl-1H-indol-2-yl)-3-oxopropanenitrile
as potent antifungal agents. Bull. Korean Chem. Soc., 2012, 33(9),
2985-2990.
19.
Sobhi M. Gomha, Khaled D.
Khalil. A Convenient ultrasound-promoted synthesis and cytotoxic activity of
some new thiazole derivatives bearing a coumarin nucleus. Molecules, 2012, 17, 9335-9347.
20.
Sobhi.
M. Gomha, Hatem A. Abdel-Aziz. Enaminones as building blocks in
heterocyclic preparations: Synthesis of novel pyrazoles, pyrazolo[3,4-d]pyridazines,
pyrazolo[1,5-a]pyrimidines, pyrido[2,3-d]pyrimidines linked to
imidazo[2,1-b]thiazole system. Heterocycles, 2012, 85(9),
2291-2303.
21.
Sobhi
M. Gomha, Sayed M. Riyadh, Ikhlass M. Abbas, Mohammed A. Bauomi.
Synthetic utility of ethylidenethiosemicarbazide: Synthesis and anti-cancer
activity of 1,3-thiazines and thiazoles with imidazole moiety. Heterocycles,
2013, 87(2), 341-356.
22.
Sobhi
M. Gomha, Hassan M. Abdel-aziz. An efficient synthesis of
functionalized 2-(heteroaryl)-3H-benzo[f]chromen-3-ones and
antibacterial evaluation. J. Chem. Res., 2013, 5, 298–303.
23.
Sobhi
M. Gomha, H. A. Abdel-Aziz. Synthesis of new
functionalized derivatives of indolo[2,3-e][1,2,4]-triazolo-[4,5-b]-1,2,4-triazine.
J. Serb. Chem. Soc., 2013, 78(80),
1119-1125.
24.
Sobhi
M. Gomha, Mohamed G. Badrey. Synthesis and antifungal evaluation of
some new heterocycles incorporating naphthalene moiety. Inter. J. of Adv. Res., 2013, 1(9), 439-446.
25.
Hassan M. Abdel Aziz, Sobhi M Gomha. Synthesis and in vitro anti-breast
cancer activity of some novel 1,4-dihydropyridine derivatives. Int. J. Pharm. Pharm. Sci., 2013, 5(3), 183-189.
26.
Sobhi
M. Gomha, Mohamed G. Badrey. A convenient synthesis of some new
thiazole and pyrimidine derivatives incorporating naphthalene moiety. J.
Chem. Res., 2013, 37(2), 86–90.
27.
Sobhi M. Gomha, Mohamed G.
Badrey. Ecofriendly regioselective one–pot synthesis of of
chromeno[4,3-d][1,2,4]triazolo[4,3-a]pyrimidine. Eur. J. Chem., 2013, 4(2), 180‐184.
28.
Sobhi
M. Gomha. Efficient catalytic synthesis, characterization and
antimicrobial evaluation of 1,4-bis(6-substituted-7-(2-arylhydrazono)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazin-3-yl)benzene
derivatives using chitosan. Int. J. Pharm.
Pharm. Sci., 2013, 5(2), 42-45.
29.
Sobhi
M. Gomha, Khaled D. Khalil, Ali M. El-Zanate, Sayed M. Riyadh. A
Facile green synthesis and anti-cancer activity of bis-arylhydrazononitriles,
triazolo[5,1-c][1,2,4]triazine, and 1,3,4-thiadiazoline. Heterocycles,
2013, 87(5), 1109-1120.
30.
Abdou O. Abdelhamid, Sobhi M. Gomha. Synthesis of new pyrazolo[1,5-a]pyrimidine,
triazolo[4,3-a]pyrimidine derivatives and thieno[2,3-b]pyridine
derivatives from sodium 3-(5-methyl-1-phenyl-1H-pyrazol-4-yl)-3-oxoprop-1-en-1-olate.
Journal of Chemistry, 2013, 2013,
ID 327095, 7 pages.
31.
Sobhi
M. Gomha, Hassan M. Abdel-aziz. Utility of
2-amino-4,5,6,7-tetrahydrobenzo [b]thiophene-3-carboxylic acid in the synthesis
of novel thieno[2,3-b][1,2,4]triazepinones and thieno[2,3-d][1,3,4]
thiadiazolo[2,3-b]pyrimidinones. Int. J. Eng. Res. and Application,
2013, 3(5), 694-700.
32.
Sobhi
M. Gomha, Hassan M. Abdel-aziz. Synthesis, reactions of
3-oxo-3-(3-oxo-3H-benzo[f]chromen-2-yl)-2-(2-phenylhydrazono) propanal,
and investigation of their antitumor activity. World J. Pharm. Pharmaceut. Sci., 2013, 2(5),
2341-2354.
33.
Sobhi M. Gomha, Taha M. A.
Eldebss, M. M. Abdulla, Abdelrahman S. Mayhoub.
Diphenylpyrroles: Novel p53 activators. Eur. J. Med. Chem., 2014, 82, 472-479.
34.
Sobhi
M. Gomha, Hatem A. Abdel-Aziz. Synthesis and antimicrobial activity
of some
pyrazolo[3',4':4,5]pyrimido[1,2-b][1,2,4]triazino[5,4-f][1,2,4,5]tetrazinone
derivatives. Inter. J. Adv. Res., 2013, 1(7), 450-457.
35.
Sobhi
M. Gomha, Kamal M. Dawood. Synthesis of novel indolizine,
pyrrolo[1,2‑a]quinoline, and
4,5‑dihydrothiophene derivatives via nitrogen ylides and their
antimicrobial evaluation. J.
Chem. Res., 2014, 38, 515-519.
36.
Eman M. H. Abbas, Sobhi M. Gomha, Thoraya A. Farghaly. Multicomponent reactions for synthesis of
bioactive polyheterocyclic ring systems under controlled microwave irradiation.
Arabian J. Chem., 2014, 7, 623-629.
37.
Sobhi
M. Gomha, Ahmad S. Shawali, Abdou O.
Abdelhamid. Convenient method for synthesis of various fused
heterocycles via utility of 4-acetyl-5-methyl-1-phenyl-pyrazole as
precursor. Turk. J. Chem., 2014, 38, 865–879.
38.
Sobhi
M. Gomha, Mohamed G. Badrey, Mohamed M. Abdalla, Reem K. Arafa.
Novel Anti-HIV-1 NNRTIs Based on a pyrazolo[4,3-d]isoxazole backbone scaffold:
Design, synthesis and exploration of molecular basis of action. Med. Chem. Commun.,
2014, 5, 1685-1692.
39.
Sobhi M. Gomha, and Sayed M. Riyadh. Multicomponent
synthesis of novel penta-heterocyclic ring systems incorporating
benzopyranopyridines scaffold. Synthesis, 2014, 46, 258-262.
40.
Mohamed G. Badrey, Sobhi M. Gomha. Synthesis and antibacterial
activity of fused isoxazole derivatives using grinding method. Int. J.
Pharm. Pharm. Sci., 2014, 6(7), 236-239.
41.
Thoraya A. Farghaly, Sobhi M. Gomha, Mohamed M. Abdalla. Synthesis
of a new series of angiotensin inhibitor and antibacterial agents. Arch.
Pharm. Res., 2014, 37, 306–314.
42.
Sobhi
M. Gomha, Taher A. Salah, Abdou O. Abdelhamid. Synthesis, characterization and
pharmacological evaluation of some novel thiadiazoles and thiazoles
incorporating pyrazole moiety as potent anticancer agents. Monatsh. Chem., 2015, 146, 149-158.
43.
Taha M. A. Eldebss, Sobhi M. Gomha, Mohamed M. Abdulla, Reem K.
Arafa. Novel pyrrole derivatives as selective CHK1 inhibitors: design,
regioselective synthesis and molecular modeling. Med. Chem. Commun., 2015, 6(5), 977-987.
44.
Ikhlass M. Abbas, Sobhi M. Gomha, Mahmoud M. Elaasser, and
Mohammed A. Bauomi. Synthesis and biological evaluation of new pyridines containing
imidazole moiety as antimicrobial and anticancer agents. Turk. J. Chem.,
2015, 39, 334- 346.
45.
Sobhi M. Gomha, Yasser H. Zaki, Abdou O. Abdelhamid. Utility
of 3-acetyl-6-bromo-2H-chromen-2-one for synthesis of new heterocycles
as potential antiproliferative
agents. Molecules, 2015, 20, 21826–21839.
46.
Sobhi M. Gomha, Sayed A. Ahmed, Abdou O.
Abdelhamid. Synthesis and cytotoxicity
evaluation of some novel
thiazoles, thiadiazoles, and pyrido[2,3-d][1,2,4]triazolo[4,3-a]pyrimidin-5(1H)-one incorporating triazole moiety. Molecules,
2015, 20, 1357-1376.
47.
Sobhi
M. Gomha, Mohamed M. Abdulla, Sahar M. Abou-Seri.
Identification of novel aminothiazole and aminothiadiazole conjugated
cyanopyridines as selective CHK1 inhibitors. Eur. J. Med. Chem., 2015,
92, 459-470.
48.
Sobhi M. Gomha, Sayed M. Riyadh, Mohamed M. Abdalla. Solvent-drop grinding method: Efficient synthesis, DPPH radical
scavenging and anti-diabetic activities of chalcones, bis-chalcones,
azolines, and bis-azolines. Curr. Org. Synth., 2015,
12(2), 220- 228.
49.
Sobhi M. Gomha, T. M. A.
Eldebss, M. G. Badrey, M. M.
Abdulla, Abdelrahman S. Mayhoub. Novel 4-heteroaryl-antipyrines as DPP-IV
Inhibitors. Chem. Biol. Drug Des., 2015,
86, 1292–1303.
50.
Sobhi
M. Gomha, Sayed M. Riyadh. Cellulose sulfuric acid as an eco-friendly
catalyst for novel one-pot synthesis of pyrido[2,3-d][1,2,4]triazolo[4,3-a]pyrimidin-5-ones.
J. Braz. Chem. Soc., 2015, 26(5), 916-923.
51.
Sobhi
M. Gomha, Hassan M. Abdel-aziz. Synthesis and antitumor activity of
1,3,4-thiadiazole derivatives bearing coumarine ring. Heterocycles, 2015, 91(3), 583-592.
52.
Ikhlass M. Abbas, Sobhi M. Gomha, Mohamed A. A. Elneairy, M. M. Elaasser,
Bazada K. A. Mabrouk. Synthesis and characterization of some novel fused thiazolo[3,2-a]pyrimidinones
and pyrimido[2,1-b][1,3]thiazinones. J. Chem. Res., 2015, 39(12), 719–723.
53.
Sobhi M. Gomha, Ikhlass M. Abbas, M.A. A. Elneairy, M. M. Elaasser, and Bazada
K. A. Mabrouk. Synthesis and biological evaluation of novel fused triazolo[4,3-a]pyrimidinones. Turk. J. Chem., 2015,
39, 510-531.
54.
Sobhi
M. Gomha, Fathy. M. Abdelrazek, Mohamed M. Abdulla. Synthesis of new
functionalized derivatives of triazolo-pyrimidine and pyrimido-thiadiazine as aromatase inhibitor. J. Chem. Res., 2015,
39(7), 425-429.
55.
Sobhi
M. Gomha, Sayed M. Riyadh, Elmahdi A. Mahmmoud, Mahmoud M. Elaasser.
Synthesis and anticancer activities of thiazoles, 1,3-thiazines, and
thiazolidine using chitosan-grafted-poly(vinylpyridine) as basic catalyst. Heterocycles, 2015,
91(6), 1227-1243.
56.
Mohamed G. Badrey, Hassan M.
Abdel-aziz, Sobhi M. Gomha,
Mohamed M. Abdalla, Abdelrahman S. Mayhoub. Design and synthesis of
imidazopyrazolopyridines as novel selective COX-2 inhibitors. Molecules, 2015,
20, 15287-15303.
57.
Ikhlass M. Abbas, Sobhi M. Gomha, M.A. A. Elneairy, M. M. Elaasser, Bazada
K. A. Mabrouk. Antimicrobial and
anticancer evaluation of novel synthetic tetracyclic system through Dimroth
rearrangement. J.
Serb. Chem. Soc., 2015,
80(10), 1251-1264.
58.
Abdou O. Abdelhamid, A. S.
Shawali, Sobhi M. Gomha, W. A.
M. A. El-Enany. Synthesis and anti-microbial evaluation of some novel thiazole,
1,3,4-thiadiazole and pyrido[2,3-d][1,2,4]-triazolo[4,3-a]pyrimidine
derivatives incorporating pyrazole moiety. Heterocycles, 2015, 91(11), 2126-2142.
59.
Kamal M. Dawood, Sobhi M. Gomha. Synthesis and anti-cancer activity of
1,3,4-thiadiazole and 1,3-thiazole derivatives having 1,3,4-oxadiazole moiety. J. Heterocycl. Chem., 2015, 52 1400-1405.
60.
Sobhi
M. Gomha, Khaled D. Khalil, Hassan M. Abdel-aziz, Mohamed M.
Abdalla. Synthesis and anti-hypertensive α-blocking activity evaluation of
thiazole derivatives bearing pyrazole moiety. Heterocycles, 2015,
91(9), 1763-1773.
61.
Abdou O. Abdelhamid, A.S. Shawali, Sobhi M. Gomha. Synthesis and reactions of N-aryl
2-aroyl hydrazono-propanehydrazonoyl chlorides with sulfur dipolarophiles. J.
Adv. Res., 2015, 6, 885-893.
62.
Abdou O. Abdelhamid, Ahmad S.
Shawali, Sobhi M. Gomha, Waleed A. M.
A. El-Enany. Synthesis and in vitro
anti-breast cancer evaluation
of some novel 1,3-thiazines and thiazolone derivatives incorporating pyrazole moiety. World J. Pharm. Pharmaceut. Sci.,
2015, 4(9), 1695-1705.
63.
Sobhi
M. Gomha, Sayed M. Riyadh, E. A. Mahmmoud, M. M. Elaasser. Synthesis
and anticancer activity of arylazothiazoles and 1,3,4-thiadiazoles using
chitosan-grafted-poly(4-vinylpyridine) as a novel copolymer basic catalyst. Chem.
Heterocycl. Compd., 2015, 51(11), 1030–1038.
64.
Sayed M. Riyadh, Sobhi M. Gomha, Elmahdi A. Mahmmoud. Recent
trends in chemistry of ethylidenethiocarbonohydrazides. Review. World J. Pharm. Pharmaceut. Sci.,
2015, 4(6), 192-201.
65.
Sobhi
M. Gomha. Bis-imidazolylpyridines as New
Antitumor Agents. World J. Pharm. Res., 2015, 4, 26-34.
66.
Sobhi M. Gomha, T. A. Salah, H. M. E. Hassaneen, H.
Abdel-aziz, M. A. Khedr. Synthesis, characterization and molecular docking of
novel bioactive thiazolyl-thiazole derivatives as promising cytotoxic antitumor
drug. Molecules, 2016, 21, 1-17.
67.
Thoraya A. Farghaly, Sobhi M. Gomha, Kamal M. Dawood, Mohamed R.
Shaaban. Synthetic routes to benzosuberone-based fused- and spiroheterocyclic
ring systems. Review. RSC Advances, 2016, 6,
17955-17979.
68.
Sobhi
M. Gomha, Mohamed G. Badrey, Mohamed M. Abdalla.
Isoxazolopyrimidinthione and isoxazolopyridopyrimidinthione derivatives: Key
intermediates for synthesis of novel fused triazoles as potent 5α-reductase
inhibitors and anti-prostate cancer. J. Heterocycl. Chem., 2016, 53, 558-565.
69.
Magda A. Abdalla, Sobhi M. Gomha, Mohamad R. Abdelaziz, Nany S. Serag,
Synthesis of some novel
thiadiazoles and thiazoles linked to pyrazole ring. Heterocycles,
2016, 92(4), 649-663.
70.
Eman M. H. Abbas, Sobhi M. Gomha, Thoraya A. Farghaly, Mohamed
M. Abdalla. Synthesis of new thiazole derivatives as antitumor agents. Curr. Org. Synth., 2016,
13(3), 456-465.
71.
Sobhi
M. Gomha, Magda A. Abdallah, Mahmoud A. Mourad, Mahmoud M. Elaasser.
Application of Mannich and Michael
reactions in synthesis of pyridopyrimido[2,1-b][1,3,5]thiadiazinones
and
pyridopyrimido[2,1-b][1,3]thiazinones as anticancer agents. Heterocycles, 2016, 92(4), 688-699.
72.
Thoraya A. Farghaly, Sobhi M. Gomha, Abdelwahed R. Sayed, Mohammed A Khedr.
Hydrazonoyl halides as precursors for synthesis of bioactive thiazole and
thiadiazole derivatives: synthesis, molecular docking and pharmacological
study. Curr. Org. Synth.,
2016, 13(3), 445-455.
73.
Sobhi M. Gomha, Mohamed G. Badrey, Mastoura M. Edrees. Heterocyclization of a bis-thiosemicarbazone
of 2,5-diacetyl-3,4-disubstituted-thieno[2,3-b]thiophene bis-1,4-phenylene-bis-thiazole derivatives and bis-1,3,4-thiadiazoles
as anti-breast cancer agents. J. Chem. Res., 2016,
40, 120-125.
74.
Sobhi M.
Gomha, F. M. Abdelrazek, Aly H. Abdelrahman, Peter Metz. Synthesis of some novel thiazole, thiadiazole
and bis-chalcones, azolines, and bis-azolines. Heterocycles,
2016, 92(5), 954-967.
75.
Sobhi
M. Gomha, Fathy M. Abdelrazek. A Facile three component-one-pot
synthesis of some novel tri-cyclic hetero-ring systems. J. Heterocycl. Chem., 2016, 53, 1892-1896.
76.
Abdelwahed R. Sayed, Sobhi M. Gomha, Thoraya A. Farghaly. Synthesis
and characterization of bis-imidazoles, bistriazoles, bis-thiadiazoles
and bis-thiazoles from novel bis-hydrazonoyl dichlorides. J. Heterocycl. Chem., 2016,
53, 255-263.
77.
Sobhi
M. Gomha, Mohamed G. Badrey, Wael A. A. Arafa.
DABCO-catalyzed green synthesis of thiazole and 1,3-thiazine derivatives linked
to benzofuran. Heterocycles, 2016, 92(8), 1450-1461.
78.
Magda A. Abdalla, Sobhi M. Gomha, Mohamad R. Abdelaziz, Nany
Serag. Synthesis and antiviral
evaluation of some novel
thiazoles and 1,3-thiazines substituted with pyrazole moiety against
rabies virus. Turk. J.
Chem., 2016,
40,
441-453.
79.
Abdou O. Abdelhamid, Sobhi M. Gomha, Nadia A. Abdelriheem, Saher M.Kandeel. Synthesis of new
3-heteroarylindoles as potential anticancer agents. Molecule, 2016,
21, 929 (1-15).
80.
Sobhi
M. Gomha, Magda A. Abdalla, Mohamad Abdelaziz, Nany Serag.
Eco-friendly one-pot synthesis
and antiviral evaluation
of pyrazolyl pyrazolines of medicinal interest. Turk. J. Chem., 2016, 40, 484-498.
81.
Thoraya A. Farghaly, Sobhi M. Gomha, Eman K. Mousa, Mahmoud Elaasser. Hydrazonoyl
chlorides in synthesis of pyrazolo[5,1-c][1,2,4]triazole derivatives and their
biological activities. J.
Chem. Res., 2016, 40, 467–470.
82.
Sobhi
M. Gomha, Thoraya A. Farghaly, Abdelwahed R. Sayed. Synthesis of
pyrazolyl pyrazoles and pyrazolyl-[1,2,4]-triazolo[3,4-d][1,5]benzothiazepines
as antimicrobial agents using hydrazonoyl chlorides. J. Heterocycl. Chem., 2016, 53,
1503-1509.
83.
Sobhi
M. Gomha, Mastoura M. Edrees, Farag
M. A. Altalbawy. Synthesis and characterization of some new bis-pyrazolyl-thiazoles
incorporating the thiophene moiety as potent anti-tumor agents. Inter. J.
Mol. Sci., 2016, 17, 1499 (1-12).
84.
Sobhi
M. Gomha, Fatma A. A. El-Hag, Ahmed M. El Defrawy, Thoraya A. Farghaly. Synthesis and
quantum chemical studies on the tautomeric structures of new thiazole and
thiadiazine derivatives. Curr. Org. Synth., 2016, 13(6), 907-916.
85.
Sobhi
M. Gomha, H. M. Abdel-aziz, K. D. Khalil. Synthesis and
SAR study of the novel thiadiazole-imidazole derivatives as new anti-cancer
agents. Chem. Pharm. Bull.,
2016, 64(9), 1356–1363.
86.
Sobhi
M. Gomha, Mohamed G. Badrey, Hamada M. Mashaly. Synthesis
and studies on chromene based reactive azo dyes and their applications on
cellulosic fibers. Eur. J.
Chem., 2016, 7), 146‐151.
87.
Sobhi M. Gomha, Nabila A.
Kheder, Abdou O. Abdelhamid, Yahia N.
Mabkhot. One pot single step synthesis and
biological evaluation of some novel bis(1,3,4-thiadiazole) derivatives
as potential cytotoxic agents. Molecules, 2016,
21, 1532(1-8).
88.
Mohamed G. Badrey, Sobhi M. Gomha, Wael A. A. Arafa, Mohamed M.
Abdulla. An approach to polysubstituted triazipines,
thiadiazoles and thiazoles based on benzopyran moiety through the utility of versatile hydrazonoyl halides
as in vitro monoamine oxidase inhibitors. J. Heterocycl. Chem., 2017, 54
(2), 1215-1227.
89.
F. M. Abdelrazek, Sobhi M. Gomha, P. Metz. Synthesis of some novel 1,4-phenylene-bis-thiazolyl
derivatives and their anti-hypertensive α-blocking activity screening. J. Heterocycl. Chem., 2017, 54, 618-623.
90.
Sobhi M. Gomha, Mastoura M. Edrees, Elham Ezz El-Arab. Synthesis and preliminary
in-vitro cytotoxic evaluation of some novel bis-heterocycles
incorporating thienothiophene. J. Heterocycl. Chem., 2017, 54, 641-647.
91.
Fatma S. Elsharabasy , Sobhi M. Gomha, Thoraya A. Farghaly, Heba S. A. Elzahabi. An efficient synthesis
of novel bioactive thiazolyl-phthalazinedione under ultrasound Irradiation. Molecules 2017, 22, 319 (1-15).
92.
Maher A. El-Hashash, Sobhi M. Gomha, Elham E. El-Arab. Utility
of pyrazolylchalcone synthon to synthesize azolopyrimidines under grindstone
technology. Chem.
Pharm. Bull.,
2017, 65, 90-96.
93.
Sayed M. Riyadh, Sobhi M. Gomha, Elmahdi A. Mahmmoud. Utility
of ethylidene-thiosemicarbazides in heterocyclic synthesis". Review. Curr. Org. Synth., 2017, 14, 3-21.
94.
Sobhi
M. Gomha, Eman M. H. Abbas, Thoraya A. Farghaly. Antimicrobial activity
of novel tetra- and penta-azaheterocyclic ring systems. J. Heterocycl. Chem., 2017, 54,
610-617.
95.
Sobhi M. Gomha, Ikhlass M. Abbas, Mahmoud M. Elaasser, Bazada K. A.
Mabrouk. Synthesis, molecular docking and pharmacological study of
pyrimido-thiadiazinones and its bis-derivatives. Letters in Drug Design &
Discovery, 2017, 14,
434-443.
96.
Sobhi M. Gomha, T. A. Farghaly, Y. N. Mabkhot, M. E. M. Zayed, Amany M. G. Mohamed.
Microwave-assisted synthesis of some novel azoles and azolopyrimidines as
antimicrobial agents. Molecules 2017, 22, 346 (1-10).
97.
Fatma A. A. El-Hag, Sobhi M. Gomha,
Thoraya A. Farghaly. Hydrazonoyl halides precursors to Synthesis of new
thiazole, thiadiazole and benzothiazepine derivatives. J. Heterocycl. Chem., 2017,
54(2), 1172-1177.
98.
Hatem M. Gaber, Mark C. Bagley, Zeinab A. Muhammad, Sobhi M. Gomha. Recent developments in chemical
reactivity of N, N-dimethylenamino ketones as synthons for various
heterocycles. Review. RSC
Advances, 2017, 7, 14562–14610.
99.
Sobhi
M. Gomha, Thoraya A. Farghaly, Abdelwahid R. Sayed. Design,
Synthesis, and characterization of bis-thiazoles based on bis-hydrazonoyl
chlorides. J. Heterocycl.
Chem., 2017, 54 (2), 1537-1542.
100. Magda A. Abdalla, Sobhi M. Gomha,
Mahmoud A. Mourad, Mahmoud M. Elaasser. Synthesis of pyridotriazolopyrimidines
as antitumor agents. J.
Heterocycl. Chem., 2017, 54(2),
1242-1251.
101. A. O Abdelhamid, Sobhi M. Gomha,
S. M. Kandeel. Synthesis of certain new thiazole and 1,3,4-thiadiazole
derivatives via the utility of 3-acetylindole. J. Heterocycl. Chem., 2017, 54,
1529-1536.
102. Sobhi
M. Gomha, Nabila A.
Kheder, M. R. Abdelaziz, Y. N. Mabkhot, and Ahmad M. Alhajoj. A facile synthesis
and anticancer activity of some novel thiazoles carrying 1,3,4‑thiadiazole
moiety. Chemistry Central J., 2017, 11, 25 (1-9).
103. Abdou O. Abdelhamid, Sobhi M.
Gomha, Nadia A. Abdelriheem. Utility of 2-(5-methyl-1-phenyl-1H- pyrazol-4-yl)-2-oxo-N'-phenylaceto-hydrazonoyl
bromide as precursor for synthesis of new functionalized heterocycles.
Synth. Commun. 2017, 47(10), 999-1005.
104. Sobhi M. Gomha,
Mohamad R. Abdelaziz, Hassan M. Abdel-aziz, Shaimaa A. Hassan. Green
synthesis and molecular docking of thiazolyl-thiazole derivatives as potential cytotoxic agents. Mini-Review
in Med. Chem., 2017, 17(9),
805-815.
105. Sobhi M. Gomha, M. M.
Edrees, R. A. M. Faty, Z. A. Muhammad, Y. N.
Mabkhot. Microwave-assisted one pot three-component synthesis of some novel
pyrazole scaffolds as potent anticancer agents. Chemistry Central J., 2017, 11, 37 (1-12).
106. Sobhi M.
Gomha, Fathy M.
Abdelrazek , Aly H. Abdelrahman, Peter Metz, Mohsen A. Sayed. A facile synthesis and
drug design of some new heterocyclic compounds incorporating pyridine moiety
and their antimicrobial evaluation. Letters in Drug Design & Discovery, 2017, 14, 752-762.
107. Sobhi M. Gomha,
Thoraya A. Farghaly, Nadia T. alqurashi, Hanaa Y. Abdou, Eman K. Mousa.
Synthesis, Molecular docking and anticancer evaluation of new arylazothiazoles. Curr. Org. Synth., 2017, 14(4), 620-631.
108. Yasser H. Zaki, Sobhi M. Gomha,
Amany M. G. Mohamed. Utility of
2-thioxo-pyrido[2,3-d]pyrimidinone in synthesis of pyridopyrimido[2,1-b][1,3,5]-thiadiazinones
and pyridopyrimido[2,1-b][1,3]thiazinones
as antimicrobial agents. Chemistry
Central J., 2017, 11, 57.
109. Abdou O. Abdelhamid, Sobhi M.
Gomha. Synthesis and
characterization of new
pyrazole based thiazoles. Synth. Commun. 2017, 47(15),
1409–1414.
110. Sobhi M. Gomha, Zeinab
A. Muhammad, Mastoura M. Edrees. Ethyl
7-methyl-1-(4-nitrophenyl)-5-phenyl-3-(thiophen-2-yl)-1,5-dihydro-[1,2,4]triazolo[4,3-a]pyrimidine-6-carboxylate.
Molbank 2017, 2017, M942; doi: 10.3390/M942.
111. Z. A. Muhammad, M. M. Edrees, R.
A. M. Faty, Sobhi M. Gomha, S. S.
Alterary, Y. N. Mabkhot. Synthesis, antitumor evaluation and molecular docking
of new morpholine based heterocycles. Molecules 2017,
22, 1211 (1-14).
112. M. A. Abdallah, Sobhi M. Gomha,
I. M. Abbas, M. S. H. Kazem, S. S. Alterary, Yahia N. Mabkhot. An Efficient synthesis
of novel pyrazole-based heterocycles as potential antitumor agents. Applied Sciences 2017, 7, 785 (1-13).
113. K. A. Rabee, Sobhi M.gomha,
A. I. Abd elfatah, Heba N. El-shemy, M. E. Shaban. Adsorption of uranium from
aqueous medium onto amino acid-modified chitosan resin. Isotope and Uranium
Research, 2017, 49(1), 93-104.
114. Sobhi M.
Gomha, Kamal M.
Dawood. Synthetic utility of pyridinium bromide: synthesis and antimicrobial
activity of novel 2,4,6-trisubstituted pyridines having pyrazole moiety. J. Heterocycl. Chem., 2017, 54
(3), 1943-1948.
115. Sobhi
M. Gomha, M. R. Abdelaziz, N. A. Kheder, H. M. Abdel-aziz, S.
Alterary, Y. N. Mabkhot. A Facile access
and evaluation of some novel thiazole and 1,3,4-thiadiazole derivatives
incorporating thiazole moiety as potent anticancer agents. Chemistry Central J., 2017, 11,105 (1-8).
116. Sobhi M. Gomha, Zeinab A. Muhammad, Hatem M. Gaber, Mohamed M. Amin. Synthesis of some novel heterocycles bearing
thiadiazoles as potent anti-inflammatory and analgesic agents. J. Heterocycl. Chem., 2017, 54(5), 2708-2716.
117. Sobhi M.
Gomha, Tamer T.
El-Idreesy, Bazada K. A. Mabrouk, Abdelwahed R. Sayed. Synthesis and characterization of new
pyrido-thieno-pyrimidine derivatives
incorporating pyrazole moiety. Synth. Commun. 2017, 17
(23), 2232-2238.
118. H. M. Gaber,
Z. A. Muhammad, Sobhi
M. Gomha, T. A. Farghaly, Mark C.
Bagley. Recent synthetic approaches to N,N-dimethyl-β-ketoenamines.
Review. Curr. Org. Chem. 2017, 21(21), 2168-2195.
119. Sobhi M.
Gomha, Maher A.
El-Hashash, M. M. Edrees, E. E. El-Arab. Synthesis, characterization and
molecular docking of novel bis-thiazolyl thienothiophene derivatives as promising cytotoxic
antitumor drug. J.
Heterocycl. Chem. 2017, 54, 2686-2695.
120. Ikhlass M. Abbas, Magda A. Abdallah, Sobhi
M. Gomha, and Mariam S. H. Kazem. Synthesis and antimicrobial activity of novel azolopyrimidines and pyrido-triazolo-pyrimidinones incorporating pyrazole moiety. J. Heterocycl. Chem., 2017, 54(6),
3447-3457.
121. Sobhi M. Gomha, M. A.
Abdallah, Salim S. Al-Showiman, M. A. Morad and Y. N. Mabkhot. Synthesis of new
pyridopyrimidinone-based thiadiazoles and pyrazolines as potential anti-breast
cancer agents. Biomedical
Research, 2017,
28 (22): 9903-9909.
122. Fathy M. Abdelrazek, Sobhi M.
Gomha, Mohamed E. B. Shaaban, Aziza I. lotfi, Heba N. El-Shemy. A facile synthesis of some novel
triazolo[3,4-b]thiadiazines and triazolo[4,3-b]tetrazines. Synth. Commun. 2018,
34(1), 32-37.
123. Abdou O. Abdelhamid, Sobhi M. Gomha, Nadia A. Abdelrehem, Ahmed M.
Shalaby, Sahar M Kandeel. Synthesis and biological evaluation of some novel thiadiazole-benzofuran hybrids
as potential antitumor agents. Synth. Commun. 2018, 48(6),
677–684.
124. Salama A. Ouf, Sobhi M. Gomha, Mohamed M. Ewies, Ihab A. A.
Sharawy. Synthesis, characterization and antifungal activity evaluation of some novel
arylazothiazoles. J. Heterocycl. Chem., 2018, 55(1),
258-264.
125. Sobhi M. Gomha, Zeinab A. Muhammad, M. R. Abdel-aziz, H.
M. Abdel-aziz, H. M. Gaber, M. M. Elaasser. One Pot Synthesis of New
thiadiazolyl-pyridines as
anticancer and antioxidant agents. J. Heterocycl. Chem., 2018, 55, 530-536.
126. Sobhi M. Gomha, Amany M. G.
Mohamed, Y.H. Zaki, M.M. Ewies, Shaaban A. Elroby. Structural elucidation and
antimicrobial evaluation of novel [1,2,4]triazolo[4,3-a]pyrimidines and
pyrido[2,3-d][1,2,4]triazolo[4,3-a]pyrimidinones. J. Heterocycl. Chem. 2018,
55, 1147-1156.
127. Sobhi M. Gomha, M. A.
Abdallah, I. M. Abbas, M. S. H. Kazem. Synthesis, cytotoxicity evaluation, molecular docking and utility of novel chalcones as
precursors for heterocycles incorporating pyrazole moiety. Med. Chem., 2018, 14(4),
344-355.
128. Sobhi M. Gomha, T. A.
Farghaly, E. M. H. Abbas, Nadia T. Alqurashi. Terephthalaldehyde: An effecient key precursor for novel synthesis of some
intresting bis-thiazoles and bis-triazolopyrimidinones. J. Heterocycl. Chem., 2018, 55, 750-755.
129. Sobhi M. Gomha, Zeinab A. Muhammad, Hassan M. Abdel-aziz, Elham Ezz El-Arab. Synthesis of new azoles and azolopyrimidines incorporating
morpholine moiety as potent anti-tumor agents. Croat. Chem. Acta
2018, 91(1), 43–51.
130. Sobhi M. Gomha, Abdou O.
Abdelhamid, Nadia A. Abdelrehem, Sahar M. Kandeel. Efficient Synthesis of new benzofuran-based thiazoles and investigation of
their cytotoxic activity against human breast carcinoma cell lines. J. Heterocycl. Chem. 2018,
55, 995-1001.
131. Sobhi M. Gomha, Zeinab A. Muhammad,
Mohamad R. Abdel-aziz, Hassan M. Abdel-aziz. Hatem M. Gaber, Mahmoud M. Elaasser.
One-pot synthesis of new thiadiazolyl-pyridines as anticancer and antioxidant
agents. J. Heterocycl.
Chem. 2018, 55, 530-536.
132. Huda R.M. Rashdan, Sobhi M. Gomha, Marwa S. El-Gendey, Maher A. El-Hashash, Abdel Mohsen M.
Soliman. Eco-friendly one-pot Synthesis of some new pyrazolo[1,2-b]phthalazinediones
with antiproliferative efficacy on human hepatic cancer cell lines. Green Chem. Lett. and Reviews, 2018, 11(3), 264–274.
133. Sobhi M. Gomha, M. S. El-Gendy, Z. A. Muhammad, A. O
Abdelhamid, M. M. Abdel-Aziz. Utility of
bis-hydrazonoyl chlorides as precursors for synthesis of new functionalized
bis-thiadiazoles as potent antimicrobial agents. J. Heterocycl. Chem. 2018,
55, 844-851.
134. Sobhi M. Gomha, M. M. Edrees, Z. A. Muhammad, Ahmed A. M. El-Reedy. 5-(Thiophen-2-yl)-1,3,4-thiadiazole derivatives: synthesis, molecular docking
and in-vitro cytotoxicity evaluation as potential anticancer agents. Drug Design, Development and
Therapy, 2018, 12, 1511-1523.
135. Salama A. Ouf, Sobhi M. Gomha, Mohamed M. Ewies, Ahmed S. Ouf,
Ihab A. Sharawy. Efficiency of newly prepared thiazole derivatives against some
cutaneous fungi.
Bioorg. Med. Chem. 2018, 26, 3287–3295.
136. Sobhi M. Gomha, Fathy M.
Abdelrazek, Aly H. Abdelrahman, Peter Metz. Synthesis of some new
pyridine-based heterocyclic compounds with anticipated anti-tumor activity. J. Heterocycl. Chem. 2018,
55, 1729-1737.
137. Fadhil B. Essa, Akram
Bazbouz, Suzan Alhilalb, Salama A. Ouf and Sobhi
M. Gomha. Synthesis and
biological evaluation of an indole core-based derivative with potent
antimicrobial activity. Res. on Chem. Intermediates, 2018,
44(9),
5345-5356.
138. Sobhi M. Gomha, Abdou O.
Abdelhamid, Omaima M. Kandil, Sahar M Kandeel, Nadia A. Abdelrehem. Synthesis
and molecular docking of some novel thiazoles
and thiadiazoles incorporating pyranochromene moiety as potent
anticancer agents. Mini-Reviews in Medicinal Chemistry, 2018, 18(19), 1670-1682.
139. Sobhi M. Gomha, Hassan M.
Abdel-aziz, Ahmed A. M. El-Reedy. Facile synthesis of pyrazolo[3,4-c]pyrazoles
bearing coumarine ring as anticancer agents. J. Heterocycl. Chem. 2018, 55(8), 1960-1965.
140. Sobhi M. Gomha, Zeinab A. Muhammad, Ahmed A. M. El-Reedy.
Intramolecular ring
transformation of bis-oxadiazoles to bis-thiadiazoles and
investigation of their anticancer activities. J. Heterocycl. Chem. 2018, 55
(10), 2360-2367.
141. Ziqi Tao, Sobhi
M. Gomha, Mohamed
G. Badrey, Tamer T. El-Idreesy, Taha M. A. Eldebss. Novel
4-heteroaryl-antipyrines: synthesis, molecular docking and evaluation as
potential anti-breast cancer agents. J. Heterocycl. Chem. 2018, 55(10),
2408-2416.
142. Mastoura M. Edrees, Sraa
Abu-Melha, Amirah M. Saad, Nabila A. Kheder, Sobhi
M. Gomha, Zeinab A Muhammad.
Eco-friendly synthesis, characterization and biological evaluation of some new pyrazolines containing thiazole moiety as potential
anticancer and antimicrobial agents. Molecules, 2018, 23, 1970 (1-13).
143. Hatem M. Gaber, Sobhi M. Gomha, Thoraya
A. Farghaly, Zeinab A.
Muhammad, Mark C. Bagley. Chemistry
of α-(arylhydrazono)-β-ketoaldehydes:
preparation and chemical reactivities. Curr. Org. Chem.
2018, 22(27), 2599-2633.
144. Fathy M. Abdelrazek, Sobhi M. Gomha,
Mohamed E. B. Shaaban, Kamal A. Rabee, Heba N. El- Shemy, Abanoub M. Abdallah,
Peter Metz. One-pot three-component synthesis and molecular docking of some
novel 2-thiazolylpyridines as potent antimicrobial agents. Mini-Reviews in
Medicinal Chemistry, 2019, 19(6), 527-538.
145. Safaa S. Hassan, Sobhi M. Gomha.
Novel functionalized thiosemicarbazone ligands and their pd(ii) complexes:
synthesis, characterization, antibacterial and cytotoxic activities. Chemical
Papers, 2019, 73 (2), 331-344.
146. Abdou O. Abdelhamid, Sobhi M. Gomha, Waleed A. M. A. El-Enany. Convenient
and efficient method for synthesis of bis-hetaryl ketones and evaluation
of their antimicrobial activity. J.
Heterocycl. Chem. 2019, 56(2), 426-433.
147. Abdou O. Abdelhamid,
Sobhi M. Gomha, Waleed A. M.
A. El-Enany. Efficient synthesis and antimicrobial evaluation of new
azolopyrimidines-bearing pyrazole moiety. J. Heterocycl. Chem. 2019, 56, 2487-2493.
148. Khaled D. Khalil, Sayed M. Riyadh, Sobhi M. Gomha, Imran
Ali. Synthesis,
characterization and application of copper oxide chitosan nanocomposite for
green regioselective synthesis of [1,2,3]triazoles. International
Journal of Biological Macromolecules. 2019,
130, 928-937.
149. Sobhi M. Gomha, M. M. Edress, Z. A. Muhammad, H.M. Gaber, M.M. Amin, Islam K. Matar. Synthesis under microwave irradiation and
molecular docking of some novel bioactive thiadiazoles. Mini-Reviews in
Medicinal Chemistry, 2019, 19(5), 437-447.
150. Abdou O. Abdelhamid, Sobhi M. Gomha. The Chemistry of
acetylpyrazoles and its utility in heterocyclic synthesis. J. Heterocycl. Chem. 2019, 56(3), 726-758.
151. Sobhi M. Gomha, Hassan M.
Abdel-aziz, Mohamed G. Badrey, Mohamed M. Abdulla. Efficient synthesis of some
new 1,3,4-thiadiazoles and 1,2,4-triazoles linked to Pyrazolylcoumarin ring
system as potent 5α-reductase inhibitors. J. Heterocycl. Chem. 2019, 56(4),
1275-1282.
152. Abdelwahed R. Sayed, Sobhi M. Gomha, Fathy M.
Abdelrazek, Mohamed S. Farghaly, Shaimaa A. Hassan, Peter Metz. Design,
efficient synthesis and molecular docking of some novel thiazolyl-pyrazole derivatives as
anticancer agents. BMC Chemistry, 2019, 13(1), 116.
153. Huda
K. Mahmoud, Refaie M. Kassab, Sobhi M. Gomha.
Synthesis and characterization of some novel bis-thiazoles. J. Heterocycl. Chem. 2019,
56, 3157-3163.
154. Hassan M. Abdel-aziz, Sobhi M. Gomha, Abdelaziz A. El-Sayed, Abdulrhman Alsayari,
Abdullatif Bin Muhsinah, Yahia Nasser
Mabkhot. Facile Synthesis and Antiproliferative Activity of New
3-Cyanopyridines. BMC Chemistry, 2019, 13(1), 137.
155. Waleed A. M. A. El-Enany, Sobhi M. Gomha, Ahmed K El-Ziaty, Wesam Hussein, Mohamed M. Abdulla,
Shaimaa A. Hassaan, Hanan A. Sallam and Rania S. Ali. Synthesis and
molecular docking of some new bis-thiadiazoles as anti-hypertensive α-blocking
agents. Synth.Commu. 2020, 50(1), 85-96.
156. Sobhi
M. Gomha, Zeinab A. Muhammad, Hassan
M. Abdel-aziz, Islam K. Matar, Abdelaziz A. El-Sayed. Green synthesis,
molecular docking and anticancer activity of novel
1,4-dihydropyridine-3,5-dicarbohydrazones under grind-stone chemistry. Green
Chem. Lett. and Reviews, 2020, 13(1), 6–17.
157. Abdelwahed
R. Sayed, Sobhi M. Gomha, Eman A.
Taher, Zeinab A. Muhammad, Hesham R. El-Seedi, Hatem M. Gaber, Mahgoub M.
Ahmed. One-Pot Synthesis of Novel Thiazoles as Potential Anti- Cancer Agents. Drug
Design, Development and Therapy, 2020, 14, 1363–1375.
158. Sobhi M. Gomha, Hassan M.
Abdel-aziz, Tariq Z. Abolibda, Shaimaa
A. Hassan, Mohamed M. Abdalla. Green synthesis, molecular docking and
pharmacological evaluation of new triazolo-thiadiazepinylcoumarine derivatives
as sedative-hypnotic scaffold. J.
Heterocycl. Chem. 2020,
57, 1034–1043.
159. Fathy M. Abdelrazek, Sobhi M. Gomha, Hassan
M. Abdel-aziz, Mohamed S. Farghaly, Peter Metz, Ahmed Abdel-Shafy. Efficient
Synthesis and In-Silico study of some novel
pyrido[2,3-d][1,2,4]triazolo[4,3-a]pyrimidine derivatives. J. Heterocycl. Chem. 2020,
57, 1759–1769.
160. Sayed, M. Riyadh, Sobhi M. Gomha. Two decades for synthesis of
mono- and bis-aminomercapto[1,2,4]triazoles. Review. RSC advances 2020,
10, 24994-25012.
161. Sobhi
M. Gomha, Zeinab A. Muhammad, Elham Ezz El-Arab, Amira M.
Elmetwally, Abdelaziz A. El-Sayed, Islam K. Matar. Design,
synthesis, molecular docking study and anti-hepatocellular carcinoma evaluation
of new bis-triazolothiadiazines. Mini-Reviews in Medicinal Chemistry,
2020, 20(9), 788-800.
162. Sraa Abu-Melha, M. M. Edrees, S. M. Riyadh, M.
R. Abdelaziz, A.A. Elfiky, Sobhi M. Gomha. Clean grinding technique: a facile synthesis and in silico
antiviral activity of hydrazones, pyrazoles, and pyrazines bearing thiazole
moiety against SARS-CoV-2 main protease (Mpro). Molecules, 2020,
25, 4565.
163. Abdelwahed R. Sayed,
Sukinah H. Ali, Sobhi M. Gomha,
Yasair S. Al-Faiyz. Review of the synthesis and biological activity of
hydrazonoyl halides. Review. Synth. Commu. 2020, 50(21),
3175–3203.
164. H.R.M. Rashdan A.H. Abdelmonsef, I.
A. Shehadi, Sobhi M. Gomha, A. Mohsen
M. Soliman, H.K. Mahmoud. Synthesis, molecular docking screening and
anti-proliferative potency evaluation of some new imidazo[2,1-b]thiazole linked
thiadiazole conjugates. Molecules, 2020, 25, 4997.
165. Salama A. Ouf, Sobhi M. Gomha, Mohamed M. Ewies, Ahmed S.
Ouf, Ihab A. A. Sharawy. Antidermatophytic activity of some newly synthesized
arylhydrazonothiazoles conjugated with monoclonal antibody. Scientific
Reports 2020, 10, 20863.
166. Abdelwahed R. Sayed, Mohamed
S. M. Ahmed, Sobhi M. Gomha. Efficient
methods for the synthesis of novel arylazothiazoles based on acetylferrocene or
adamantane. Current Organic Synthesis 2020, 17 (4), 282-287.
167. M. Shaban, Sobhi M. Gomha,
Synthesis and Characterization of Nano Au/NPAA Templates. JESC. 2020,
II (2), 147-155.
168. Sobhi M. Gomha, H. A. Abdelhady, D.
Z. H. Hassain, A. H. Abdelmonsef, M. El-Naggar, Mahmoud M. Elaasser, Huda K.
Mahmoud. Thiazole based thiosemicarbazones:
synthesis, cytotoxicity evaluation and molecular docking study. Drug
Design, Development and Therapy, 2021, 15, 659–677.
169. Mohammad Alhilal, Yaser
A. M. Sulaiman, Suzan Alhilal, Sobhi M. Gomha,
Salama A. Ouf. Antifungal activity of new diterpenoid alkaloids isolated by
different chromatographic methods from Delphinium peregrinum L. var. eriocarpum
Boiss. Molecules, 2021, 26, 1375.
170. Sraa Abu-Melha, Zeinab A.
Muhammad, Amr S. Abouzid, Mastoura M. Edrees, Ahmed S. Abo Dena, Sara Nabil, Sobhi M. Gomha. Multicomponent Synthesis, DFT
Calculations and Molecular Docking Studies of Novel Thiazolyl-Pyridazinones as
Potential Antimicrobial Agents Against Antibiotic-Resistant Bacteria. J.
Molecular Structure 2021, 1234,130180.
171. L. A. Alshabanah, Sobhi M. Gomha, L. A. Al-Mutabagani, T. Z.
Abolibda, N. A. Abd El-Ghany, W.A. M. A. El-Enany, A. K El-Ziaty, R. S. Ali, N.
A. Mohamed. Cross-Linked Chitosan/Multi-Walled Carbon Nanotubes Composite as
Ecofriendly Biocatalyst for Synthesis of Some composite as Ecofriendly Biocatalyst
for Synthesis of Some Novel Benzil Bis-Thiazoles. Polymers, 2021,
13, 1728.
172. Abdelwahed R. Sayed, Hany M Abd
El-lateef, Sobhi M. Gomha, Tariq
Z.Abolibda. L-Proline catalyzed green synthesis and anticancer evaluation of
novel bioactive benzil bis-hydrazones under grinding technique. Green Chem.
Lett. and Reviews, 2021, 14 (2), 179–188.
173. Laila A. Al-Mutabagani, Latifah A.
Alshabanah, Sobhi M. Gomha, Hoda A.
Ahmed. Synthesis, thermal and optical characterizations of new lateral organic
systems. Crystals 2021, 11(5), 551.
174. Abeer S. Altowyan, Hoda
A. Ahmed, Sobhi M. Gomha, Ayman M. Mostafa. Optical and thermal
investigations of New Schiff base/ester Systems in pure and mixed states. Polymers,
2021, 13, 1678.
175. F. M. Abdelrazek, Sobhi M. Gomha, M. S.
Farghaly, Peter Metz. One-pot,
three-component synthesis of pyrido[2,3-d]pyrimidinones using aluminate
sulfonic acid nanocatalyst under grinding technique. Polycyclic
Aromatic Compounds 2020, 41(7), 1472-1482.
176. Abdelwahed R. Sayed, Sobhi M.
Gomha, K. Shalabi, Hany Abd El-Lateef. Synthesis and study of
poly[(hydrazinylazo)]thiazoles as potent corrosion inhibitors for cast
iron-carbon alloy in molar HCl: A collective computational and experiential
methods. Journal of Molecular Liquids, 2021, 337, 116555.
177. Huda K. Mahmoud, Sobhi M. Gomha, Thoraya
A. Farghaly, Hanem M. Awad. Synthesis of thiazole Linked thiazolo[2,1-b]thiazoles
as antitumor agents. Polycyclic Aromatic Compounds 2021, 41(8),
1608–1622.
178. Sobhi M. Gomha, Hoda
A. Ahmed, Mohamed Shaban, Tariq Z. Abolibda, Muna S. Khushaim and Khalid A.
Alharbi. Synthesis, Optical Characterizations and Solar Energy Applications of
New Schiff Base Materials. Materials 2021, 14, 3718.
179. Sraa Abu-Melha, Sobhi M. Gomha,
A. S. Abouzied, M. M. Edrees, A. S. Abo Dena, Z. A. Muhammad.
Microwave-assisted one pot three-component synthesis of novel bioactive
thiazolyl-pyridazinediones as potential antimicrobial agents against
antibiotic-resistant bacteria. Molecules 2021, 26, 4260.
180. Fowzia S. Alamro, Sobhi M. Gomha,
Mohamed Shaban, Abeer S. Altowyan, Tariq Z. Abolibda, Hoda A. Ahmed. Optical
investigations and photoactive solar energy applications of new synthesized
Schiff base liquid crystal derivatives. Scientific Reports 2021, 11,
15046.
181. Latifah A. Alshabanah, Laila A. Al-Mutabagani, Sobhi M. Gomha, Hoda A. Ahmed, Saheed A. Popoola, Mohamed Shaban. Novel
sulphonic acid liquid crystal derivatives; experimental, computational and
optoelectric characterizations. RSC Advances, 2021, 11,
27937-27949.
182. Abeer S. Altowyan, Hoda A. Ahmed, Sobhi
M. Gomha, Tariq Z. Abolibda, Mohamed Shaban. Optical investigations
and photoactive solar energy applications of new synthesized Schiff base liquid
crystal derivatives. Scientific Reports 2021, 11, 15046.
183. Huda K. Mahmoud, Ashraf A. Abbas, Sobhi
M. Gomha. Synthesis, antimicrobial
evaluation and molecular docking of
new functionalized bis(1,3,4-thiadiazole) and bis(thiazole) derivatives. Polycyclic
Aromatic Compounds 2021, 41(9), 2029–2041.
184. R. M. Kassab, Sobhi M. Gomha,
Z. A. Muhammad, A. S. El-khouly. Synthesis, biological profile, and molecular
docking of some new bis-fused imidazole templates and investigation of their
cytotoxic potential as anti-tubercular and/or anticancer prototypes. Medicinal
Chemistry 2021, 17(8), 875-886.
185. Sraa Abu-Melha, Mastoura M. Edrees, Sobhi
M. Gomha, Sayed M. Riyadh, Waleed A. M. A. El-Enany, Aboubakr H.
Abdelmonsef. Bioactive scaffolds: synthesis and in silico antibacterial
activity of bis-azoles and N-bridged bis-fused azoles. Der Pharmacia Lettre 2021,
13, 67-78.
186. Fowzia S. Alamro, Hoda A. Ahmed, Saheed A. Popoola, Hamud A. Altaleb, Khulood A. Abu Al-Ola, Sobhi M. Gomha.
Effect of the relative
positions of di-laterally substituted Schiff base derivatives: Phase transition
and computational investigations. Crystals 2021, 11, 870.
187. Sobhi M. Gomha, Hoda
A. Ahmed, Mohamed Shaban, Tariq Z. Abolibda, Khalid Abdulaziz Alharbi, Hafsa H.
Alalawy. New nematogenic conical‑shaped supramolecular H‑bonded complexes for
solar energy investigations. Scientific Reports 2021, 11,
17622.
188. Fowzia S. Alamro, Hoda A. Ahmed, Sobhi M. Gomha, Mohamed Shaban. Synthesis, mesomorphic
and solar energy characterizations of new non-symmetrical Schiff base Systems. Front.
Chem. 2021, 9, 686788.
189. Refaie M. Kassab, Sobhi M. Gomha,
Sami A. Al-Hussain, Ahmed S. Abo Dena, Marwa M. Abdel-Aziz, Magdi E. A. Zaki,
Zeinab A. Muhammad. Synthesis and in-silico studies of new bis-thiazole
derivatives and their preliminary antimicrobial activity. Arabian J. Chem.
2021, 14, 103396.
190. Laila A. Al-Mutabagani, Fathy M. Abdelrazek, Sobhi M. Gomha, Ali S. Hebishy, Mohamed S.
Abdelfattah, Safaa M. Hassan, Abdelwahed
R. Sayed and Mahmoud M. Elaasser.
Synthesis and Biological Evaluation of Thiazolyl-ethylidene hydrazino-thiazole
Derivatives: A Novel Heterocyclic System. Applied Sci. 2021, 11,
8908.
191. Sobhi
M. Gomha, Mastoura M. Edrees, Zeinab A. Muhammad, Nabila A.
Kheder, Sraa Abu-Melha, Amirah M. Saad. Synthesis, characterization and
antimicrobial evaluation of some new 1,4-dihydropyridines-1,2,4-triazole hybrid
compounds. Polycyclic
Aromatic Compounds 2020, https://doi.org/10.1080/10406638.2020.1720751.
192. W. A. M. A. El-Enany, Sobhi M. Gomha, W. Hussein, H.A. Sallam, R. S. Ali and Ahmed K
El-Ziaty. Synthesis and biological evaluation of some novel bis-thiadiazoles
as antimicrobial and antitumor
agents. Polycyclic Aromatic Compounds 2020, https://doi.org/10.1080/10406638.2019.1709874.
193. Sobhi M. Gomha, Zeinab
A. Muhammad, Sami A. Al-Hussain, Magdi E. A. Zaki, Hassan M. Abdel-aziz.
Synthesis, Characterization and antimicrobial evaluation of some new 1,4-dihydropyridine
hybrid with 1,3,4-thiadiazole. Polycyclic Aromatic Compounds 2020,
DOI: 10.1080/10406638.2020.1804410.
194. Abdelwahed R. Sayed, Sobhi M. Gomha, Yasair S. Al-Faiyz, Yasser H.
Zaki. New convenient routes of hydrazonoyl halides for the synthesis of novel
thiazoles and polythiazoles. Polycyclic Aromatic Compounds 2020, doi:
https://doi.org/10.1080/10406638.2020.1866032.
195. Laila A. Al-Mutabagani, Latifah A. Alshabanah, Sobhi M. Gomha, Tariq Z. Abolibda, Mohamed
Shaban, Hoda A. Ahmed. Synthesis, mesomorphic and electrical investigations of
new furan liquid crystal derivatives. Front. Chem., 16 September 2021
| https://doi.org/10.3389/fchem.2021.711862,
196. S. Abu-Melha, S. M. Gomha, M. M. Edrees, N. A. Kheder, A. M.
Saad, S. M. Riyadh, M. M. Abdel-Aziz, and M. A. Abdelmoaz. Synthesis and
Anti-tubercular (Tb) Evaluation of Bis-[4-ethylidineamino
[1,2,4]triazole-3-thiol] tethered by 1,4-Dihydropyridine. Russian Journal of
Bioorganic Chemistry, 2021, in press.
197. Mohammad Alhilal,
Yaser A.M Sulaiman, Suzan Alhilal, Sobhi M.
Gomha, Salama A. Ouf. Synthesis of Novel Acyclic Nucleoside Analogue
Starting From 6-Aminouracil as Potent Antimicrobial Agent. Polycyclic
Aromatic Compounds 2021, in press.
198. Hany M. Abd El-Lateef, K. Shalabic, Abdelwahed R. Sayed, Sobhi M. Gomha, Esam M. Bakir. The novel
polythiadiazole polymer and its composite with α-Al(OH)3 as
inhibitors for steel alloy corrosion in molar H2SO4:
experimental and computational evaluations Journal of Industrial and
Engineering Chemistry, 2021, in press.
199. Huda K. Mahmoud, Sobhi M. Gomha,
Hyam A. Abdelhady, Mahmoud M. Elaasser, Doaa Z. H. Hassain Microwave-Assisted
One-Pot Three component Synthesis of Some Thiazolyl(hydrazonoethyl)thiazoles as
Potential Anti-breast Cancer AgentsPolycyclic Aromatic Compounds 2021,
in press.
200. Mohammad Alhilal, Suzan Alhilal, Sobhi
M. Gomha, Salama A. Ouf. Isocarpine as A New Peperidine Alkaloid
From Adenocarpus Complicatus With Anticandidal Activity. Natural Product Journal 2021, in
press.
PUBLISHED
BOOKS
1.
Sobhi
M. Gomha, Sayed M. Riyadh. Synthesis of some new bioactive
heterocycles. LAP Lambert Academic Publishing, 2020, ISBN: 978-620-0-78484-1.
2.
Sobhi
M. Gomha, Sayed M. Riyadh, Elmahdi A. M. Abubaker. Synthesis and
Biological Evaluation of Some New Pyrroles. LAP Lambert Academic Publishing, 2020,
ISBN: 978-620-0-78618-0.
3.
Sobhi
M. Gomha, Amany Mohamed, Kareem Mohamed. Synthesis and Antimicrobial
Evaluation of New Fused Azines. LAP Lambert Academic Publishing, 2020, ISBN: 978-620-2-51329-6.
4.
Sobhi
M. Gomha, Abdou Abdelhamid, Sahar Kandeel. Synthesis of Some Novel
Bioactive Indoles as Anticancer Agents. LAP Lambert Academic Publishing, 2020,
ISBN: 978-620-2-51660-0.
5. Sobhi M. Gomha, Fathi M. Abdelrazek and, Heba N.
El-Shemy. Synthesis of Some Novel Bioactive Fused 1,2,4-Triazole. LAP
Lambert Academic Publishing, 2020, ISBN: 978-620-2-52077-5.
6.
Sobhi M. Gomha, Aziza I. lotfi, Heba N. El-Shemy. Extraction
of Uranium and Thorium Ions from Acidic Solutions. LAP Lambert Academic Publishing,
2020, ISBN: 978-620-2-52075-1.
7.
Abdou Abdelhamid, Sobhi M. Gomha, S. Kandeel. Synthetic
Approaches for Bioactive Compounds from Khellin and Visnagin. LAP Lambert
Academic Publishing, 2020, ISBN: 978-620-2-51661-7.
8.
Sobhi
M. Gomha, Mohammed A. Bauomi. Synthesis and Biological Evaluation of
Some New Imidazoles. LAP Lambert Academic Publishing, 2020, ISBN: 978-620-2-51432-3.
9. Sobhi
M. Gomha, Abdou O. Abdelhamid, Waleed El-Enany. New Synthetic Strategy for Synthesis of Novel pyrazoles. LAP Lambert Academic Publishing, 2020, ISBN: 978-620-2-52077-5.
10.
Sobhi M. Gomha, Magda A. Abdallah, Mahmoud
Metwally. Pyridopyrimidines:
Synthesis and Biological Activity. LAP
Lambert Academic Publishing, 2020, ISBN:
978-620-2-52529-9.
11. Sobhi M. Gomha, Magda
A. Abdallah, Ikhlass M. Abbas. Pyrazoles: Synthesis and Biological Activity. LAP Lambert Academic Publishing, 2020, ISBN: 978-620-2-52530-5.
لأخogle Schoolar: https://scholar.google.com.eg/citations?user=ZDOss_wAAAAJ&hl=en&oi=ao
· Scopus:http://orcid.org/0000-0001-6744-7817 ID: 6506724900 https://www.scopus.com/authid/detail.uri?authorId=6506724900
· Research gate: https://www.researchgate.net/profile/Sobhi_Gomha3
· Orcide ID: http://orcid.org/0000-0002-7739-2837
- - I awarded the prize of the best paper in heterocyclic chemistry
from the Egyptian Heterocyclic Chemistry Society (E.H.C.S) for 2015.
- - I was included in the list of the World's Top 2% Scientists by Stanford University in 2019. https://elsevier.digitalcommonsdata.com/datasets/btchxktzyw/1
- - I was included in the list of the World's Top 2% Scientists by Stanford University in 2020 (I awarded the 1st rank in Organic Chemistry in Cairo University). https://elsevier.digitalcommonsdata.com/datasets/btchxktzyw/2
- - I was included in the list of the World's Top 2% Scientists by Stanford University in 2021(I awarded the 1st rank in Organic Chemistry in Cairo University). https://elsevier.digitalcommonsdata.com/datasets/btchxktzyw/3
- - In 2021: I awarded the 2nd rank in Organic Chemistry (Cairo University) and 4th rank (Egypt) according to World Scientists and University Ranking 2021 (AD Scientific Index). https://www.adscientificindex.com/scientist.php?id=90816
- - I awarded certificates of appreciation from Cairo University for distinguished scientific publication for the years 2008-2020.
- - I awarded certificates of appreciation from Cairo University for distinguished scientific publishing (more than 10 research papers) for the years 2015: Top 10 publishers in Cairo University, Egypt.
- - I awarded certificates of appreciation from Cairo University for distinguished scientific publishing (more than 10 research papers) for the years 2016: Top 10 publishers in Cairo University, Egypt.
- - I awarded certificates of appreciation from Cairo University for distinguished scientific publishing (more than 10 research papers) for the years 2017: Top 10 publishers in Cairo University, Egypt.
- - I awarded certificates of appreciation from Cairo University for distinguished scientific publishing (more than 10 research papers) for the years 2018: Top 10 publishers in Cairo University, Egypt.
- - I awarded certificates of appreciation from Cairo University for distinguished scientific publishing (more than 10 research papers) for the years 2019: Top 10 publishers in Cairo University, Egypt.
- - I awarded certificates of appreciation from Cairo University for distinguished scientific publishing (more than 10 research papers) for the years 2020: Top 10 publishers in Cairo University, Egypt.
- - Eco-friendly synthesis, characterization and biological evaluation of some novel pyrazolines containing thiazole moiety as potential anticancer and antimicrobial agents (2017-2018) and funding agency: the Deanship of Scientific Research (GRP‑68‑39) King Khalid University, KSA.
- -
The separation of rare earth elements from the
beach monazite metal from the black sand for the field season 2017-2018 and
approved by Resolution No. 497 of 2017. Funding agency: Nuclear Materials Authority, Kattameya, Egypt.
- -
Green
synthesis and biological evaluation of some novel thiazole-based heterocycles
as potential anticancer agents (2019-2020) and funding agency: the Deanship of Scientific Research (Project
Number 1811008) King Faisal University, KSA.
- -
Green
synthesis of some novel thiazole-based heterocycles as anti-cancer agents
(2019-2020) and funding agency: the
Deanship of Scientific Research (Project Number Takamel 11-86) Islamic
University of Madinah, KSA.
- -
Synthesis
of Innovative Optical Organic Compounds (2020-2021) and funding agency: the Deanship of Scientific Research (the
Program of research project funding after publication, Project Number
PRFA-P-42-8) Princess Nourah bint Abdulrahman University, KSA.
- -
Green
synthesis of some novel heterocyclic compounds as anti-cancer agents
(2020-2021) and funding agency: the
Deanship of Scientific Research (the program of research project funding after
publication, Project Number PRFA-P-42-9) Princess Nourah bint Abdulrahman University,
KSA.
- -
Green
synthesis of some novel thiazole-based heterocycles as anti-cancer agents
(2019-2020) and funding agency: the
Deanship of Scientific Research (Project Number Takamel 11-86) Islamic
University, KSA.
- -
Synthesis
of Photo-active Innovative organic compounds to improve the photovoltaic and
electrical properties of solar cells (2020-2021) and funding agency: the Deanship of Scientific Research (Project
Number Tammay 2-654) Islamic University of Madinah, KSA.